Results 171 to 180 of about 19,801,094 (386)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Publisher Correction: New reconstruction of the Wiwaxia scleritome, with data from Chengjiang juveniles

Scientific Reports, 2023
Zhifei Zhang, Martin R. Smith, Degan Shu
doaj   +1 more source

Early life disadvantage and adult adiposity: tests of sensitive periods during childhood and behavioural mediation in adulthood [PDF]

, 2018
Stephen E. Gilman, Yen‐Tsung Huang, Marcia Pescador Jimenez, Golareh Agha, Su H. Chu, Charles B. Eaton, Risë B. Goldstein, Karl T. Kelsey, Stephen L. Buka, Eric B. Loucks   +9 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Morphological Evolution and Extinction of Eodiscids and Agnostoid Arthropods

Life
The temporal range of eodiscids and agnostoid arthropods overlaps with several early Paleozoic geological events of evolutionary significance. However, the responses of agnostids to these events and how the perturbations associated with them (both ...
Huarui Li, Tao Dai, Yanlong Chen, Chunling Xue, Luke C. Strotz   +4 more
doaj   +1 more source

Inhibition of adult neurogenesis reduces avoidance behavior in male, but not female, mice subjected to early life adversity

, 2022
Renée C. Waters, Hunter M. Worth, Betsy Vasquez, Elizabeth Gould   +3 more
openalex   +1 more source

Interaction between early-life pet exposure and methylation pattern of ADAM33 on allergic rhinitis among children aged 3-6 years in China [PDF]

, 2021
yu zhang, Meiyu Tan, Xiaoqiong Qian, Cong Li, Lei Yue, Yuehong Liu, Song Shi   +6 more
openalex   +1 more source

Early Childhood Experiences: Laying the Foundation for Health Across a Lifetime [PDF]

, 2008
Outlines current research on how factors such as parents' education, income, and race/ethnicity affect children's development and health throughout life, as well as how early childhood development programs can mitigate socioeconomic ...
Paula Braveman, Susan Egerter, Tabashir Sadegh-Nobari   +2 more
core  

Obesity and early life [PDF]

Obesity Reviews, 2007
openaire   +3 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source