Results 251 to 260 of about 19,801,094 (386)

Early-life neural correlates of behavioral inhibition and anxiety risk. [PDF]

Neuropsychopharmacology
Filippi CA, Massera A, Xing J, Martinez Agulleiro L.   +3 more
europepmc   +1 more source

Early-life adversity and neurological disease: age-old questions and novel answers

Nature Reviews Neurology, 2019
Annabel K. Short, T. Baram
semanticscholar   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Early life environment moderates association of body composition and internalizing problems in adolescence. [PDF]

Commun Psychol
Buss C, Graham AM, Gyllenhammer LE, Wadhwa PD, Rasmussen JM.   +4 more
europepmc   +1 more source

Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes [PDF]

, 2019
Raúl F. Pérez, Pablo Santamarina‐Ojeda, Juan Ramón Tejedor, Rocío G. Urdinguio, Julio Álvarez‐Pitti, Pau Redón, Agustín F. Fernández, Mario F. Fraga, Empar Lurbe   +8 more
openalex   +1 more source

Evidence for early life in Earth’s oldest hydrothermal vent precipitates

Nature, 2017
Matthew S. Dodd, D. Papineau, T. Grenne, J. Slack, M. Rittner, F. Pirajno, J. O’Neil, C. Little   +7 more
semanticscholar   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Early-Life Socialization Enhances Social Competence and Alters Affiliative Preference in Piglets. [PDF]

Animals (Basel)
Luo L, Li Z, Bolhuis JE, Wang Y, Wu D, Li Y, Li C.   +6 more
europepmc   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

The impact of early-life rearing conditions on the porcine gut microbiota and immune system. [PDF]

Anim Microbiome
Comer L, Akram MZ, Zhao H, Huo P, Arévalo Sureda E, Xiao C, Usman HUK, Siegien P, Wavreille J, Aerts J, Everaert N.   +10 more
europepmc   +1 more source