Results 151 to 160 of about 4,774,290 (284)

Natural product‐derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges

British Journal of Pharmacology, EarlyView.
Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang, Hio Lam Ho, F. David Horgen, Andrea Fleig, Zhong‐Ping Feng, Hong‐Shuo Sun   +5 more
wiley   +1 more source

The interplay of attachment styles and early maladaptive schemas across different populations. [PDF]

BMC Psychol
Yu J, Osback C, Bekerian DA.
europepmc   +1 more source

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation‐Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis

Cell Proliferation, EarlyView.
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang, Feifan Chang, Siliang Ge, Fuming Cao, Pincong Fu, Haobo Zhang, Ming Chen, Yi Li, Peifu Tang, Pengbin Yin   +9 more
wiley   +1 more source

Differential Transdiagnostic Relevance of Early Maladaptive Schemas Across Personality Traits and Psychopathological Symptoms. [PDF]

Personal Ment Health
Major J, Matuz A, Gács B, Birkás B.
europepmc   +1 more source

Psychoeducational schema therapy for psoriasis and atopic dermatitis: a randomized controlled pilot crossover trial

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Atopic dermatitis and psoriasis are chronic inflammatory skin diseases often linked to psychological stress. Integrative care models are lacking. This randomized pilot study aimed to develop and test a psychoeducational intervention for dermatology patients.
Regina von Spreckelsen, Hila Emmert, Jan Hartmann, Matthias Hübenthal, Stephan Weidinger, Ulrich Mrowietz, Eva M. J. Peters, Sascha Gerdes   +7 more
wiley   +1 more source

Gender Differences in Preoperative Anxiety and the Association with Early Maladaptive Schemas: A Cross-Sectional Correlational Study. [PDF]

Healthcare (Basel)
Abdelrazek MN, Mohamed HMM, El-Monshed AH, Morsy OMI, Khedr MA, Almegewly WH, Alanezi S, Mahmoud LS.   +7 more
europepmc   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Profiles of distress related to sexual function, psychological distress, and sexual pleasure: a person-centered analysis of early maladaptive schemas and psychological inflexibility. [PDF]

Sex Med
Santos VP, Rosa PJ, Roberto MS, Manão AA, Oliveira C, Tomada N, Osur J, Telles-Correia D, Pascoal PM.   +8 more
europepmc   +1 more source

Early Maladaptive Schemas in Opiate and Stimulant Users

, 2015
Objectives: Early maladaptive schemas are valid representations of unpleasant childhood experiences that shape a person’s viewpoints of the world, and lead to clinical symptoms such as depression, personality disorders, and substance abuse.
Ameneh Oji, Omid Massah, Zahra Karami, Ali Farhoudian   +3 more
core  

The epigenetic landscape of skeletal muscle in response to exercise and aging

The FEBS Journal, EarlyView.
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley   +1 more source