Results 221 to 230 of about 4,392 (296)

Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi, Azadeh Niknejad, Elaheh Amini   +2 more
wiley   +1 more source

Sociocultural Implications in the Development of Early Maladaptive Schemas in Adolescents Belonging to Sexual and Gender Minorities. [PDF]

Int J Environ Res Public Health
Cardoso BLA, Lima AFA, Costa FRM, Loose C, Liu X, Fabris MA.   +5 more
europepmc   +1 more source

Adverse Childhood Experiences and Deviant Behaviour Among University Students: Exploring the Roles of Self‐Regulation and Age

Mental Health Science, Volume 4, Issue 2, June 2026.
ABSTRACT The present study investigated the association between ACE and deviant behaviour among students, with moderating roles of self‐regulation and age. In a cross‐sectional design, 420 students were surveyed using ACE, deviant behaviour, and self‐regulation scales.
Inuusah Mahama
wiley   +1 more source

Trait Characteristics, Exposure to Abusive Dating Behaviours and Paranoia in a Sample of British Adults

MultiPsych, Volume 1, Issue 2, June 2026.
ABSTRACT This cross‐sectional correlational survey study uses the vulnerability‐stress model to examine interactions between trait characteristics and exposure to abusive dating behaviours (ghosting, breadcrumbing, gaslighting and coercion) and their associations with paranoia.
Barbara Lopes, Rusi Jaspal
wiley   +1 more source

The importance of examining early maladaptive schemas in the diagnosis and treatment of obsessive-compulsive disorder. [PDF]

Front Psychiatry
Csigó K, Münnich Á, Molnár J.
europepmc   +1 more source

Integrating Transdiagnostic and Biopsychosocial Approaches to Move Beyond Categorical Diagnoses in Neurodevelopmental Disorders: A Perspective Review

PsyCh Journal, Volume 15, Issue 3, June 2026.
ABSTRACT Neurodevelopmental disorders (NDD) represent a heterogeneous group of conditions that are thought to be related to impaired brain development, which often leads to significant functional difficulties across various domains. According to the Diagnostic and Statistical Manual of Mental Disorders (DSM) and the International Statistical ...
Duo Liu, Shu Liu, Lirong Luo
wiley   +1 more source

Unraveling Online Mental Health Through the Lens of Early Maladaptive Schemas: AI-Enabled Content Analysis of Online Mental Health Communities. [PDF]

J Med Internet Res
Ang BH, Gollapalli SD, Du M, Ng SK.
europepmc   +1 more source

Vascular Immune Remodeling: A CD4+ T Cell–Driven Immune Trajectory Associated With Arterial Stiffness

Aging Cell, Volume 25, Issue 6, June 2026.
This study integrated arterial stiffness with peripheral TCRβ repertoire and single‐cell transcriptomics in adults without cardiovascular disease, revealing a CD4+ T cell–driven “vascular immune remodeling” trajectory distinct from classical immunosenescence: increased TCR diversity, broad expansion of low‐frequency public clones and virus‐associated ...
Yu Miao, Bangwei Chen, Changqing Zeng, Xiaofen Wu, Minglei Yang, Cuntai Zhang, Jianguo Zhang, Yutao Du, Tao Li, Lei Ruan   +9 more
wiley   +1 more source

Understanding early maladaptive schemas in autistic and ADHD individuals: exploring the impact, changing the narrative, and schema therapy considerations. [PDF]

Front Psychol
Spicer L, DeCicco E, Clarke A, Ambrosius R, Yalcin O.   +4 more
europepmc   +1 more source

Senescent BMSC‐Derived Thbs1 Drives Inflammaging and Impairs Bone Regeneration by Suppressing PINK1/Parkin‐Mediated Mitophagy in Macrophages

Aging Cell, Volume 25, Issue 6, June 2026.
Aging BMSC‐derived Thbs1 activates the macrophage TGF‐β/Smad3 pathway to transcriptionally repress Pink1, impairing mitophagy and causing mitochondrial ROS accumulation. This redox imbalance drives M1 polarization and IL‐6 secretion. IL‐6 feeds back to BMSCs via the JAK/STAT3 pathway to inhibit osteogenesis and upregulate Thbs1, establishing a self ...
Yifeng Xing, Jingjing Su, Yanjun Lin, Nengwen Huang, Sihui Zhang, Yuwei Zhou, Jie Lu, Weiping Chen, Kaixun He, Wenxiu Yuan, Yang Li, Geyuan Zheng, Pengyuan Hu, Dong Wu, Yanjing Ou, Jiang Chen   +15 more
wiley   +1 more source