Results 41 to 50 of about 16,479 (293)

Parental Bonding and Early Maladaptive Schemas [PDF]

Journal of Psychological Abnormalities in Children, 2013
Objective:Attachment bonds are present throughout one’s life and affect interpersonal relationships. Specifically, parent-child relationship is a key factor in the development of personality. Similarly, childhood experiences can lead to configuration and stabilization of cognitive patterns, which play an equally important role in the development and
openaire   +1 more source

Early Maladaptive Schemas and Schema Modes in clinical disorders: A systematic review

Psychology and Psychotherapy: Theory, Research and Practice, 2023
Abstract Purpose Although schema therapy has been predominantly applied to treat personality disorders, interest into its application in other clinical disorders is growing. Central to schema therapy are Early Maladaptive Schemas (EMS) and Schema Modes.
Andreas Bär, Hannah E. Bär, Marleen M. Rijkeboer, Jill Lobbestael   +3 more
openaire   +3 more sources

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Explaining the Structural Model of Social Anxiety Based on Early Maladaptive Schemas and Family Performance

Novelty in Biomedicine, 2020
Background: The purpose of study was to determine the mediation role of early maladaptive schemas in the relationship between family performance and social anxiety features of students.
Himan Naderzadeh, Mahdieh Salehi, Marjan Ja’fari Roshan, Roya Kochak Entezar   +3 more
doaj   +1 more source

The Inter-Structural Relationships between Early Maladaptive Schemas and Marital Commitment of Couples: The Mediating Role of Communication Patterns [PDF]

, 2021
Background: Marital commitment has been identified as one of the effective components in the development and stability of marital relationships. This study aimed to investigate the inter-structural relationships between early maladaptive schemas and ...
Alizadeh Mousavi 2, Ebrahim, Jajarmi 1*, Mahmoud, Mehrpouya 1, Fahime   +2 more
core   +2 more sources

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Differential Transdiagnostic Relevance of Early Maladaptive Schemas Across Personality Traits and Psychopathological Symptoms. [PDF]

Personal Ment Health
ABSTRACT The Alternative Model for Personality Disorders in DSM‐5 conceptualizes personality pathology using dimensional trait domains, yet the cognitive mechanisms underlying these traits remain insufficiently understood. Early maladaptive schemas (EMSs) represent enduring cognitive–affective structures that may contribute to both personality ...
Major J, Matuz A, Gács B, Birkás B.
europepmc   +2 more sources

Irgm1 Improves Postinfarction Cardiac Repair by Promoting Neutrophil Clearance and Efferocytosis

Advanced Science, EarlyView.
The Irgm1‐PDIA3 axis enhances post‐infarction cardiac repair by accelerating neutrophil clearance and facilitating efferocytosis. Irgm1 holds potential as a prognostic biomarker in MI, and LOC14 may represent a therapeutic option to improve cardiac repair, especially in cases of Irgm1 deficiency.
Zeng Wang, Lai Wei, Mingyang Wang, Shanjie Wang, Lili Xiu, Jiaxiang Sun, Rongzhe Lu, Yige Liu, Jiaxin Wang, Fengyi Liu, Weike Liu, Bo Yu, Yong Sun, Xueqin Gao, Shaohong Fang   +14 more
wiley   +1 more source

Investigating the Relationship between Rumination and Negative Affect with Early Maladaptive Schemas in Students [PDF]

, 2023
Introduction: Early maladaptive schemas are one of the most important psychological characteristics, and rumination and negative affect are important variables related to primary maladaptive schemas.
Asadi, Masoud, Bazargani, Maedeh, Moraveji, Mahtab   +2 more
core   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

Advanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source