From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2019 Raisin Maturity Study 1982RAI 12.1; RAI 12.3; RAI 12.2Early Maturity Studies1976_16CAL-RAB Early Maturity Studies ...
Dokoozlian, Nick K. Jr. +7 more
core
A study on relationship between morphological and agronomic traits, and seed cotton yield and early-maturity in different cultivars [PDF]
فیزیولوژی محیطی گیاهی, 2006 The relationships between the seed cotton yield and early maturity with to traits of 8 cotton cultivars were studied at plant Institiute, Gorgan, Iran in 2004.
M Dadashi,, B Kazerani
doaj
Identification of genetic loci for early maturity in spring bread wheat using the association analysis and gene dissection. [PDF]
PeerJ, 2023 Kiseleva AA +4 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The At Issue Maturity of Corporate Bonds: The Influence of Credit Rating, Security Level, Duration and Macreoconomic Conditions [PDF]
We examine the determinants of the at issue time to maturity of corporate bonds. We find evidence that corporations partly determine the at issue maturity of bonds by responding to economic conditions.
Geetajali Bali, Frank Skinner
core
FAIR Data Maturity Model. Specification and Guidelines
, 2020 Findability, Accessibility, Interoperability and Reusability – the FAIR principles – intend to define a minimal set of related but independent and separable guiding principles and practices that enable both machines and humans to find, access ...
FAIR Data Maturity Model Working Group
core +1 more source
Changes in the physicochemical properties of isolated starch and plantain (Musa AAB Simmonds) flours for early maturity stage. [PDF]
Heliyon, 2023 Torres-Vargas OL +4 more
europepmc +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source