Results 221 to 230 of about 806,379 (302)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Genomic-assisted refinement of heterotic groups in short-duration maturing tropical yellow and orange maize inbred lines. [PDF]

BMC Agric
Adejumobi II, Mengesha W, Gedil M, Meseka S, Abubakar AM, Bonkoungou OT, Ouattara F, Badu-Apraku B, Menkir A, Derera J, Mushoriwa H.   +10 more
europepmc   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Toward Advanced Sensing and Data-Driven Approaches for Maturity Assessment of Indeterminate Peanut Cropping Systems: Review of Current State and Prospects. [PDF]

Sensors (Basel)
Sahayaraj SRE, Chandel AK, Jjagwe P, Vennam RR, Balota M, Manimozhian A.   +5 more
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Pore Evolution Mechanisms in the Longmaxi Formation Shale Reservoir of the Anchang Syncline under Basin-Mountain Tectonic Evolution. [PDF]

ACS Omega
Zhao Y, Wang Y, Zhang H, Chen S, Chen H, Wang H, Zhang J.   +6 more
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Genetic Diversity Analysis of 96 <i>Gossypium hirsutum</i>-<i>Gossypium barbadense</i> Introgression Lines and Early Maturing Northern China Cotton Lines Using a 40K Liquid-Phase Chip. [PDF]

Genes (Basel)
Chen P, Yang Y, Fang J, Yu H, Dong Y, Zhao Z, Tian Y, Xie Z, Li Y.   +8 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Effect of Transgenic Cotton with Bt Event Mpp51Aa2 on Cotton Fleahopper (<i>Pseudatomoscelis seriatus</i>) During Early Cotton Growth and Resulting Plant Injury. [PDF]

Insects
Alwedyan MA, Bradicich PA, McGinty JA, Brewer MJ.   +3 more
europepmc   +1 more source