Results 121 to 130 of about 5,057,518 (281)

Occult serous tubal intraepithelial carcinoma and high‐grade serous carcinoma at risk‐reducing salpingo‐oophorectomy in BRCA1/2 carriers: A Czech two‐center cohort

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Risk‐reducing salpingo‐oophorectomy is the standard intervention for prevention of tubo‐ovarian carcinoma in women with pathogenic BRCA1/2 variants, yet the optimal timing remains clinically challenging, particularly for BRCA2 carriers.
Olga Zikan Dubova, Lukas Dostalek, Michal Emingr, Munachiso Ndukwe, Michal Zikan   +4 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

CARDIOVASCULAR RISK STRATIFICATION IN WOMEN WITH EARLY OESTROGEN DEFICIENCY

Российский кардиологический журнал, 2010
The paper is focused on the problems of cardiovascular risk stratification in women with early oestrogen deficiency (manifested before the age of 45 years).
N. G. Vardugina, T. A. Azarenkova
doaj  

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Age at menopause and its association with comorbidities in older women

Russian Open Medical Journal
Background — Menopause age is a potential mediator of subsequent mortality, morbidity, and quality of life after menopause. Objective — Since limited studies have reported an association between age at menopause and chronic diseases in the elderly ...
Ali Bijani, Fatemehzahra Hossein Nia, Seyed Reza Hosseini, Simin Mouodi   +3 more
doaj   +1 more source

Menopause and big data: Word Adjacency Graph modeling of menopause-related ChaCha data

, 2017
OBJECTIVE: To detect and visualize salient queries about menopause using Big Data from ChaCha. METHODS: We used Word Adjacency Graph (WAG) modeling to detect clusters and visualize the range of menopause-related topics and their mutual proximity ...
Julie L. Otte, Wendy R. Miller, Miller, Wendy, Chen X. Chen, Chen, Chen X., Doyle Groves, Otte, Julie L., Janet S. Carpenter, Carpenter, Janet S., Groves, Doyle   +9 more
core   +1 more source

Dose–Response Relationship Between Triglyceride Glucose‐Waist Height Ratio Index and Cardiometabolic Multimorbidity Among Chinese Middle‐Aged and Older People

Journal of Clinical Laboratory Analysis, EarlyView.
Using data from 6674 middle‐aged and older Chinese adults in the China Health and Retirement Longitudinal Study (CHARLS), this study investigated the association between the triglyceride glucose‐waist height ratio (TyG‐WHtR) index and cardiometabolic multimorbidity (CMM).
Lingling Li, Zongliang Yu, Yixuan Feng, Changxin Sun, Lanqing Hu, Xinyi Liu, Liang Li, Min Wu, Longtao Liu   +8 more
wiley   +1 more source

The Long-term Health Effects of Early Menopause

Although the average age of menopause in western women is 50 years, 10% of women experience menopause between the age of 40 and 44 (early menopause) and 2 to 3% before the age of 40 (premature ovarian insufficiency).
Savukoski, Susanna M, Niinimäki, Maarit
core   +1 more source

Transperineal Ultrasound in Chronic Pelvic Pain: A Systematic Review

Journal of Clinical Ultrasound, EarlyView.
Graphical abstract illustrating the systematic review process and highlighting key pelvic floor musculature (PFM) alterations detected by transperineal ultrasound (TPU) in patients with chronic pelvic pain (CPP) and associated conditions. These findings provide insights to enhance understanding and management of CPP.
Giulia Paoni Saccone, Noemi Tonti, Valeria Gangale, Maria Grazia Porpora, Federica Tomao, Violante Di Donato, Innocenza Palaia, Giusi Santangelo, Ludovico Muzii, Giuseppe Rizzo, Giorgia Perniola   +10 more
wiley   +1 more source

Reproductive Characteristics, Postmenopausal Obesity, and Cardiovascular Disease Incidence in the Women's Health Initiative

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Early menarche, menopause, and short reproductive lifespan are risk factors for cardiovascular disease (CVD), but whether these reproductive characteristics are independently associated with CVD or influenced by obesity is unclear.
Jaclyn D. Borrowman, Hailey Banack, Claire Cook, Erin S. LeBlanc, Aladdin H. Shadyab, Bernhard Haring, Hind A. Beydoun, Matthew Nudy, Matthew Allison, Lisa W. Martin, Peter F. Schnatz, Mercedes R. Carnethon, Amanda M. Perak, Sadiya S. Khan, Deepika Laddu   +14 more
doaj   +1 more source