Results 51 to 60 of about 5,057,518 (281)

Symptoms of Early Onset of Menopause in Women, A Cross-Sectional Study in District Shaheed Benazirabad [PDF]

Liaquat National Journal of Primary Care
Background: Early menopause is a significant public health concern as the reproductive health of women gets affected and predisposed to early risk, psychological, sexual, and other disorders, poor bone health, and chronic diseases.
Imran Mirbahar, Hanna Khair Tunio, Renuka Lohana, Nisha Kumari, Komal Jhamandas, Kanchan, Devyani Tehlwani   +6 more
doaj   +1 more source

Understanding menopause

, 2023
This report presents findings from research which aimed to understand issues around menopause at the university of Westminster, in order to better to support staff at the university going through menopause.
Cartwright, T., Clark, P., Cheshire, A.
core   +1 more source

Bone Marrow Macrophage STING Signaling is a Direct Nexus Linking Marrow Adipose Expansion to NAD+ Depletion and Osteogenic Decline in Skeletal Aging

Advanced Science, EarlyView.
This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li, Kuanhui Gao, Mengjie Wang, Songlin Liang, Dandan Li, Guoqing Tan, Haipeng Xue, Yujie Liu, Peng Zhang, Zhanwang Xu, Wenxiang Cheng, Yongjun Wang, Nianhu Li   +12 more
wiley   +1 more source

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Sarcopenia and Sarcopenic Obesity in Postmenopausal Women: Limitations of BMI as a Predictor of Sarcopenic Obesity

AGING MEDICINE, EarlyView.
The prevalence of sarcopenia and sarcopenic obesity is large among community‐dwelling postmenopausal women, and lower body mass index is a significant predictor of both. The finding that low body mass index predicts both sarcopenia and sarcopenic obesity, highlights the limitation of body mass index as a measure of adiposity in the assessment of ...
Remya Rajan, Kripa Cherian, Thomas Paul, Hesarghatta Shyamasunder Asha, Arun Jose, Grace Rebekah, Nihal Thomas, Nitin Kapoor   +7 more
wiley   +1 more source

Early Menopause in Type 2 Diabetes – A Study from a South Indian Tertiary Care Centre [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Menopause marks the end of ovarian function and it is called ‘early’ or ‘premature’ if it occurs before 45 years. Very little is known about the menopause transition in Diabetic women.
T.V.D. Sasi Sekhar, Soumya Medarametla, Arifa Rahman, Satya Sahi Adapa   +3 more
doaj   +1 more source

A core outcome set for genitourinary symptoms associated with menopause: the COMMA (Core Outcomes in Menopause) global initiative.

, 2021
OBJECTIVE Genitourinary symptoms, such as vaginal dryness and pain with sex, are commonly experienced by postmenopausal women. Comparing treatments for these genitourinary symptoms are restricted by the use of different outcome measures in clinical ...
Bell, Robin J, Vincent, Amanda, Maki, Pauline M, Nappi, Rossella E, Hickey, Martha, Kiesel, Ludwig, Christmas, Monica, Khandelwal, Sunila, Mitchell, Caroline M, Iliodromiti, Stamatina, Simon, James A, Jaisamrarn, Unnop, Goldstein, Steven R, Niederberger, Craig, Wolfman, Wendy, Hillard, Tim, Hunter, Myra S, Davis, Susan R, Giblin, Karen, Shifren, Jan, Kim, Bobae V, Stute, Petra, Roberts, Helen, Panay, Nick, Carpenter, Janet S, Lumsden, Mary Ann, Lensen, Sarah   +26 more
core   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Early menarche, nulliparity and the risk for premature and early natural menopause [PDF]

Human Reproduction, 2017
Are parity and the timing of menarche associated with premature and early natural menopause?Early menarche (≤11 years) is a risk factor for both premature menopause (final menstrual period, FMP
Mishra, GD, Pandeya, N, Dobson, AJ, Chung, H-F, Anderson, D, Kuh, D, Sandin, S, Giles, GG, Bruinsma, F, Hayashi, K, Lee, JS, Hizunuma, H, Cade, JE, Burley, VJ, Greenwood, DC, Goodman, A, Kildevaeld Simonsen, M, Adami, H-O, Demakakos, P, Weiderpass, E   +19 more
openaire   +9 more sources

Hyperostosis frontalis interna: Observed patterns, prevalence, and dementia associations in older adults

The Anatomical Record, EarlyView.
Abstract Hyperostosis frontalis interna (HFI) is a frequently underrecognized condition characterized by overgrowth of the frontal endocranium, most commonly observed in post‐menopausal women. Although its etiology remains unclear, hormonal influences and a possible relationship with neurocognitive changes have been proposed.
Danielle Felsberg, Kira Morgan, Rickey‐Levon Burch, Madelyn Furr, Zachary Tyson, Steven Lesh   +5 more
wiley   +1 more source