Results 211 to 220 of about 1,361,869 (313)

Everyday executive functions in children with neurofibromatosis type 1: Data from nine institutions. [PDF]

Neuropsychology
Zong X, Liu D, Wu X, Wolters PL, Payne JM, Klein-Tasman BP, Walsh KS, Janusz J, Pride N, Morris SM, Bearden CE, Stavinoha PL, Hou Y.   +12 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Brain volume trajectories in young children are associated with polygenic scores for late-onset Alzheimer's disease risk. [PDF]

Alzheimers Dement
Kundu P, Zhu C, Huentelman M, Deoni SCL, Naymik M, Taguinod F, De Both M, Lewis CR, Müller HG.   +8 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Global burden of esophageal cancer attributable to smoking and alcohol, 1990-2021, with projections to 2040: a population-based analysis of the global burden of disease study 2021. [PDF]

Ann Med
Zhou H, Wu J, Yin Y.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Quelques sondages stratigraphiques dans les cartulaires de Lagrasse et de Lézat (IXe - Xes.) : une langue entre latin tardif et premier occitan

Archéopages
Michel Banniard
doaj   +1 more source

Prevalence and Trends in Cardiovascular Risk Factors Among Middle-Aged South Asian Adults Compared With Other Racial and Ethnic Groups in the United States: A Longitudinal Analysis of 2 Cohort Studies. [PDF]

J Am Heart Assoc
Pedamallu H, Aghabazaz Z, Lancki N, Rodriguez LA, Siddique J, Moorthy M, Shah NS, Allen NB, Kanaya AM, Kandula NR.   +9 more
europepmc   +1 more source