Results 221 to 230 of about 284,976 (311)

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya   +2 more
wiley   +1 more source

Risks and Benefits of Feeding Enterostomy Creation During Minimally Invasive Esophagectomy: A Propensity‐Weighted Analysis Using the Japanese National Clinical Database

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Feeding enterostomy during MIE was evaluated in 19 054 patients from the Japanese NCD using propensity weighting. Enterostomy was associated with higher reoperation and respiratory complications, but lower delayed gastric emptying and deep vein thrombosis, with no significant difference in overall bowel obstruction.
Eisuke Booka   +7 more
wiley   +1 more source

Early Eocene Palynofloral Diversity and <i>Nothofagus</i> Niche Modeling Across Western Gondwana. [PDF]

open access: yesPlants (Basel)
Hinojosa LF   +4 more
europepmc   +1 more source

Automation of Surgical Workflow Recognition: Unveiling the Surgical Instrument Kinematics that Underly Robot‐Assisted Prostatectomy Procedures

open access: yesAdvanced Intelligent Discovery, EarlyView.
Automated procedural analysis is recognized as one of the major game changers for robotic surgery. Meaning digital analysis needs to replace the manual assessments that set todays standard. Mechanical robotic‐instrument tracking enables the derivation of quantitative kinematic metrics that support behavior‐based workflow segmentation into distinct ...
Kateryna Pirkovets   +4 more
wiley   +1 more source

Advanced Experiment Design Strategies for Drug Development

open access: yesAdvanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang   +3 more
wiley   +1 more source

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