Hemodynamics Beyond Ischemic Zone Underlies Early Neurological Deterioration in Minor Stroke with Large Vessel Occlusion [PDF]
Early neurological deterioration (END) occurs in a substantial proportion of minor stroke patients with large vessel occlusion or severe stenosis (LVO/SS) and is a strong predictor of poor outcome, yet its underlying mechanisms remain debated.
Zhijiao He +21 more
doaj +4 more sources
Prediction model for early neurological deterioration in large artery atherosclerotic stroke [PDF]
BackgroundTo develop and validate a predictive model for early neurological deterioration (END) in acute ischemic stroke due to large artery atherosclerosis.MethodsWe included 433 patients admitted to our hospital between August 2023 and January 2025 ...
Lele Feng +5 more
doaj +4 more sources
Association of low-dose intra-arterial plus intravenous tirofiban with improved functional outcome in branch atheromatous disease-related stroke patients with early neurological deterioration [PDF]
Background Management of early neurological deterioration (END) in branch atheromatous disease (BAD)-related stroke remains challenging, and intravenous (IV) tirofiban’s efficacy is limited.
Xinxiu Liu, Miao Wu, Zhiyong Zhang
doaj +3 more sources
Early Neurological Deterioration in Subcortical Infarcts: A Narrative Review [PDF]
Background/Objectives: Early neurological deterioration (END) is a frequent and clinically relevant complication in patients with a single small subcortical infarction (SSI), including lacunar infarction and branch atheromatous disease (BAD).
Juan José Mengual +4 more
doaj +2 more sources
Background and PurposeHyperglycemia has been associated with unfavorable outcome of acute ischemic stroke, but this association has not been verified in patients with endovascular thrombectomy treatment.
Zheng Dai +13 more
doaj +3 more sources
Correction: Association of infarct volume with early neurological deterioration in ischemic stroke patients undergoing endovascular treatment. [PDF]
Hu J +9 more
europepmc +5 more sources
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH [PDF]
Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients.
Zuoqiao Li +10 more
doaj +2 more sources
Prediction of early neurological deterioration using quantitative susceptibility mapping in small artery occlusion ischemic stroke [PDF]
Background: Approximately 20–30% of ischemic stroke patients with small artery occlusion (SAO) experience early neurological deterioration (END) after stroke onset, which is associated with a poor prognosis.
Xuelian Tang +3 more
doaj +2 more sources
Objectives To investigate the effects of early administration of tirofiban after intravenous thrombolysis on early neurological deterioration in patients with branch atheromatous disease.
Bin Liu +6 more
doaj +2 more sources
Development and validation of a machine learning model based on multi-source clinical data for predicting the risk of early neurological deterioration in patients with ischemic stroke. [PDF]
Li Y +5 more
europepmc +3 more sources

