Results 191 to 200 of about 31,348 (253)

Postnatal interaction of size and shape in the human endocranium and brain structures. [PDF]

J Anat
Takagi K, Kondo O.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Deep-sea fish reveal an alternative developmental trajectory for vertebrate vision. [PDF]

Sci Adv
Fogg LG, Isari S, Barnes JE, Patel JS, Marshall N, Salzburger W, de Busserolles F, Cortesi F.   +7 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Does intraspecific variation in juvenile Late Cretaceous ammonoids correlate with their systematic position, longevity and paleogeography? [PDF]

Swiss J Palaeontol
Tajika A, Iida T, Wani R, Landman NH, Ikuno K, Klug C.   +5 more
europepmc   +1 more source

PBPK Modeling of Acetaminophen in Pediatric Populations: Incorporation of SULT Enzyme Ontogeny to Predict Age-Dependent Metabolism and Systemic Exposure. [PDF]

Life (Basel)
Sharma S, Taft DR.
europepmc   +1 more source

Developmental trajectories of cognitive traits in meerkats match socio-ecological demands

Saccà T, Protopapa E, Jaeggi AV, Forss SIF.   +3 more
europepmc   +1 more source

Feminization of sex-biased gene expression in a parthenogenetic stick insect suggests unresolved sexual antagonism in early development

Djordjevic J, Labédan M, Schwander T, Parker DJ.   +3 more
europepmc   +1 more source