Results 41 to 50 of about 38,188 (301)

Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis

Nature Communications, 2023
The early ontogeny of hematopoietic niches is largely unknown. This article shows that the sclerotome compartment of somites provides Alcam and Pdgfr-α dependent mesenchymal cells that are essential at every step of the development of hematopoiesis.
Emi Murayama, Catherine Vivier, Anne Schmidt, Philippe Herbomel   +3 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Characterisation and ontogeny of natural killer cells in Xenopus laevis [PDF]

, 2002
The initial aim of the work described in this Thesis was to investigate the lymphoid organ distribution, phenotype and function of the lymphocyte population identified by candidate anti-Xenopus natural killer (NK) cell monoclonal antibodies (mAb's ...
Stewart, Rebecca
core  

Productional data of primiparous dairy cows reared in different social environments during the first 8 weeks after birth

Data in Brief, 2022
This paper is composed of 5 datasets describing primiparous milk production, reproduction, body weight, activity and whole life longevity and reproductional data in dairy cows that had been reared either with or without mother for the first four days ...
Barbora Valníčková, Radka Šárová, Ilona Stěhulová   +2 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

The genetic interaction of REVOLUTA and WRKY53 links plant development, senescence, and immune responses.

PLoS ONE, 2022
In annual plants, tight coordination of successive developmental events is of primary importance to optimize performance under fluctuating environmental conditions.
Justine Bresson, Jasmin Doll, François Vasseur, Mark Stahl, Edda von Roepenack-Lahaye, Joachim Kilian, Bettina Stadelhofer, James M Kremer, Dagmar Kolb, Stephan Wenkel, Ulrike Zentgraf   +10 more
doaj   +1 more source

Bone histology of Neogene angulate tortoises (Testudines: Testudinidae) from South Africa: palaeobiological and skeletochronological implications

Royal Society Open Science, 2023
Here we examine the tibial microstructure of modern and fossil angulate tortoises to assess the histology and growth from the late Miocene–early Pliocene, Pleistocene through to modern forms.
Mohd Shafi Bhat, Anusuya Chinsamy, John Parkington   +2 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Rethinking the ontogeny of mindreading

, 2006
We propose a mentalistic and nativist view of human early mental and social life and of the ontogeny of mindreading. We define the mental state of sharedness as the primitive, one-sided capability to take one's own mental states as mutually known to an ...
Colle, Livia, Bosco, Francesca M., Bosco, Francesca Marina, Tirassa, Maurizio   +3 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source