Results 21 to 30 of about 245,615 (252)

Exploring Risk Factors for Early Pregnancy Loss: A Retrospective Hysteroscopy Study in a Single Institution

Clinical and Experimental Obstetrics & Gynecology
Background: To explore the risk factors for early pregnancy loss and to study the relationship between early pregnancy loss and intrauterine adhesion (IUA) confirmed by hysteroscopy.
Chaoxia Cao, Xiaoli Liu, Yinan Chen, Xiujun Yang, Bin Peng, Zhouying Hu, Qin Zhou   +6 more
doaj   +1 more source

Recurrent pregnancy loss, psychological distress and wellbeing support for women: a mixed-methods analysis

BMC Women's Health
Background Research suggests multiple experiences of miscarriage, also known as recurrent pregnancy loss (RPL), may be associated with compounded risk for adverse mental health impacts.
Áine Aventin, Martin Robinson, Jonathan White, Martina Galeotti   +3 more
doaj   +1 more source

Lower rate of early pregnancy loss in patients experiencing early-onset low LH in GnRH antagonist cycles supplemented with menotropin

Journal of the Formosan Medical Association, 2019
Background/Purpose: The role of LH during controlled ovarian stimulation (COS) in the general population remains contentious. There is no consensus on the indications for LH supplementation during COS.
Po-Kai Yang, Ming-Yih Wu, Kuang-Han Chao, Chin-Hao Chang, Mei-Jou Chen, Shee-Uan Chen   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Risk factors for early pregnancy loss in women with obesity

Фундаментальная и клиническая медицина
Aim. To study clinicopathological risk factors for early pregnancy loss in women with obesity.Materials and Meth­ods. Here we examined 130 patients with early pregnancy loss: 69 women with obesity and 61 patients with healthy body weight.Results.
E. A. Kuzmina, A. A. Orazmuradov, Zh. Zh. Suleymanova, I. V. Bekbaeva, A. A. Apresyan, A. N. Akhmatova, A. A. Orazmuradova   +6 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Knights in shining armour and (M)others in life jackets: Women’s experiences of advocating for care alone when suffering recurrent early pregnancy loss during the SARS-CoV-2 pandemic

BMC Public Health
Background Recurrent early pregnancy loss [rEPL] is a traumatic experience, marked by feelings such as grief and depression, and often anxiety. Despite this, the psychological consequences of rEPL are often overlooked, particularly when considering ...
Flora E. Kent-Nye, Kayleigh S. Sheen, Karen Burgess, Munira Oza, Laura A. Magee, Davor Jurković, Sergio A. Silverio   +6 more
doaj   +1 more source

Selected non-somatic risk factors for pregnancy loss in patients with abnormal early pregnancy

Annals of Agricultural and Environmental Medicine, 2015
Introduction and objective Spontaneous abortion constitutes one of the most frequent complication of human pregnancy. Despite intensive research efforts undertaken to date, the etiopathogenesis of early pregnancy loss has not been fully elucidated.
Maciej Paszkowski, Piotr Czuczwar, Sławomir Woźniak, Monika Paszkowska, Piotr Szkodziak, Krzysztof Patyra, Tomasz Paszkowski   +6 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source