Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis [PDF]
Baeten, Dominique +9 more
core
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu +13 more
wiley +1 more source
The evaluation of effectiveness of IL-17 and IL-23 inhibitors on nail and enthesis involvement in early psoriatic arthritis patients by high-frequency ultrasonography: a single-centre prospective proof-of-concept study. [PDF]
Ruscitti P +12 more
europepmc +1 more source
ABSTRACT Background Machine learning (ML) is increasingly used to analyse pain‐related data, emphasising how well variables classify individuals, that is, training an algorithm to assign people to predefined groups such as high versus low pain sensitivity, rather than focusing on p‐values.
Jörn Lötsch +2 more
wiley +1 more source
Low apolipoprotein A1 and high apolipoprotein B levels indicate specific lipid changes in treatment naïve early psoriatic arthritis. [PDF]
Ishchenko A +7 more
europepmc +1 more source
ABSTRACT We report a 69‐year‐old man diagnosed as myelodysplastic syndrome and administrated with azacitidine and selinexor treatment. Then he was revealed high fever and multiple tender erythematous papules involving his mouth, back, upper and lower extremities, which were diagnosed as Sweet's syndrome by skin biopsy.
Liya Ma +7 more
wiley +1 more source
Determinants of radiographic progression in early psoriatic arthritis: insights from a real-world cohort. [PDF]
Koc GH +13 more
europepmc +1 more source
Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu +4 more
wiley +1 more source
Higher Synovial Immunohistochemistry Reactivity of IL-17A, Dkk1, and TGF-β1 in Patients with Early Psoriatic Arthritis and Rheumatoid Arthritis Could Predict the Use of Biologics. [PDF]
Pinto-Tasende JA +6 more
europepmc +1 more source
The Scientific Case for Animal Models: A Perspective From Musculoskeletal Researchers
ABSTRACT The National Institutes of Health (NIH) has launched a major initiative to expand human‐based New Approach Methodologies (NAMs) in biomedical research and reduce reliance on animal models. While NAMs offer powerful complementary tools, animal‐based research remains indispensable in musculoskeletal science for understanding complex cellular and
Michael Hadjiargyrou +4 more
wiley +1 more source

