Results 51 to 60 of about 30,812 (239)

Does Early Tracheostomy Improve Outcome in Severe Head Injury?

, 2022
Object:  To determine if early tracheostomy reduces the duration of mechanical ventilation, Intensive Care Unit (ICU) stay and morbidities associated with it in patients with severe head injury.
SYED ATHER ENAM, MUHAMMAD ZUBAIR TAHIR
core  

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Early versus late tracheostomy for critically ill patients: A clinical evidence synopsis of a recent Cochrane Review [PDF]

, 2016
Although a general range has been recognized, evidence-based practice has yet to determine the optimal timing for tracheostomy during intubation. This article provides a synopsis of eight randomized controlled trials, including almost 2000 patients ...
Allison Keeping
core  

Short-term Outcome of Early Tracheostomy in the Trauma Patients Admitted to Intensive Care Unit: A Comparative Study [PDF]

Bulletin of Emergency and Trauma, 2013
Objectives: To compare the results of early versus late tracheostomy in trauma patients admitted to intensive care unit (ICU).Methods: This was case control study being performed at a major trauma centre in Shiraz, Iran including120 trauma patients ...
Bijan Ziaeian, Sedigheh Tahmasebi, Hadi Niakan, Afsoun Fazelzadeh   +3 more
doaj   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Early versus late tracheostomy in cardiovascular intensive care patients

, 2016
Background: Benefits of tracheostomy have been well established. Most of the literature, refers these benefits to general intensive care population, excluding cardiac surgery or including only small number of these patients.
Jerath, Angela; Department of Anesthesia and Pain Management, Toronto General Hospital/University Health Network; Department of Anesthesia, Faculty of Medicine, University of Toronto, Canada, Puentes, Wilfredo; Department of Anesthesia and Pain Management, Toronto General Hospital, Canada, Cabrerizo Sanchez, Rosa; Department of Anesthesia and Pain Management, Toronto General Hospital, Canada, Wąsowicz, Marcin; Department of Anesthesia and Pain Management, Toronto General Hospital/University Health Network; Department of Anesthesia, Faculty of Medicine, University of Toronto, Canada, Djaiani, George; Department of Anesthesia and Pain Management, Toronto General Hospital/University Health Network; Department of Anesthesia, Faculty of Medicine, University of Toronto, Canada   +4 more
core   +1 more source

Early Versus Late Tracheostomy in Mechanically Ventilated COVID-19 Patients: A Comparative Study

Acta Medica Iranica, 2023
The decision to perform tracheostomy during the COVID-19 pandemic has been based mainly on practical and empirical standards. Also, the amount of scientific evidence to determine the exact timing of tracheostomy in patients with severe COVID-19 on ...
Samrand Fattah Ghazi, Nima Nazari, Mohammad Taghi Beigmohammadi, Masoud Ramezani, Mohammadreza Salehi, Yeganeh Abedipour   +5 more
doaj   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio, Annabelle Wilcox, Stacey Cole, Josue Flores Daboub, José E. Morales Moreno, Kasey G. Andrews, S. Yukiko Asaki, Thomas A. Pilcher, Martin Tristani‐Firouzi, Mary C. Niu, David Viskochil, Benjamin Hammond   +11 more
wiley   +1 more source

Elective tracheostomy during COVID-19 outbreak: to whom, when, how? Early experience from Venice, Italy [PDF]

, 2021
Purpose: The need for prolonged invasive mechanical ventilation in COVID-19 patients is placing the otorhinolaryngologist in front of an increasing request for tracheostomy.
Battel I., Michieletto L., Lazzari F., Zennaro B., Spinato R., Volo T., Bellin M., Spinato G., Busatto C., Politi D., Stritoni P.   +10 more
core   +1 more source

Milestone Attainment in Young Children With Arthrogryposis Multiplex Congenita: Developmental Profile and Associated Factors

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Evidence on developmental milestones in children with arthrogryposis multiplex congenita (AMC) under the age of five is scarce. This multisite cross‐sectional study described developmental status and examined factors associated with milestone attainment in 143 children aged 0–66 months from a pediatric AMC Registry.
Ahlam Zidan, Sophia C. Pasia, Emmanouil Rampakakis, Reggie Hamdy, Frank Rauch, Lauren C. Hyer, Joel Lerman, Haluk Altiok, Krister Freese, Cary Mielke, Sarah B. Nossov, Philip F. Giampietro, Thania Ordaz‐Robles, Noémi Dahan‐Oliel   +13 more
wiley   +1 more source