Results 221 to 230 of about 985,100 (309)

SharpCEEWPServer: A Lightweight Server for the Communication Protocol of China Earthquake Early Warning Systems. [PDF]

Sensors (Basel)
Li L, Li J, Xiang W, Liu Z, Liao W, Zhang L.   +5 more
europepmc   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Hierarchical Channeled Graphitized Nanoarchitecture as a Diagnostic Platform for Maternal Fever Warning

Advanced Science, EarlyView.
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin, Ning Li, Heyuhan Zhang, Xufang Hu, Zhiqiang Liu, Chunhui Deng   +5 more
wiley   +1 more source

Feasibility and efficacy of a psychological graded early warning and intervention system for hospitalised patients in a general hospital. [PDF]

Front Med (Lausanne)
Duan Y, Geng W, Zhu B, Shi L, Cao J, Li T, Sun R, Qu W, Xiao C, Xie Y, Li J, Du J, Hu J, Jiang Y, Wei J.   +14 more
europepmc   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

Advanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo, Ying Yang, Zizhen Fu, Fengqi Liu, Susu Fang, Kele Xu, Shanshan Wang   +6 more
wiley   +1 more source

A machine learning-driven early warning system for cryptocaryoniasis in marine aquaculture. [PDF]

Parasit Vectors
Xie X, Zhang B, Wang X, Jiang Y, Buchmann K, Zhou S, Li Y, Yin F, Galindo-Villegas J.   +8 more
europepmc   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Supporting the implementation of a Maternal Early Warning System (MEWS) protocol using Human-Centred Design. [PDF]

BMC Health Serv Res
Mc Intyre D, Spiegel A, Kapellas S, Ghali B, Mazzietti K, Fortune RL, Haas S, Cérat S, Sugars E, Campbell-Clarke K, Deliscar S, Mehdizadeh M, Williams N, Awwad F, Stimson M, Wan M, Lawford K, Tatum A, Tunde-Byass M, Tresierra M, Simon D, Finch R, Maxwell C, Nielssen I, Morency AM, Frew M, Vedam S, D'Souza R, Malhamé I.   +28 more
europepmc   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Physics-based earthquake early warning using distributed acoustic sensing. [PDF]

Sci Rep
Ben-Zeev S, Lior I.
europepmc   +1 more source