Results 231 to 240 of about 6,266,241 (291)

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Can the Early Warning Score (ANDC) Predict Tocilizumab Efficacy in Patients with COVID-19 Cytokine Storm? [PDF]

Eur J Rheumatol
Kılıç Ö, Tecer D, Kaya MN, Çınar M, Yılmaz S.   +4 more
europepmc   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Application of Modified Early Warning Score System (MEWS) in the Assessment of Disease Condition and Prognosis of Patients After Neurosurgical Procedure or Intervention. [PDF]

Risk Manag Healthc Policy
Liu P, Xu J, Liu Y, Wang X, Tan Q, Wang Y.   +5 more
europepmc   +1 more source

Modifications to the National Early Warning Score: a scoping review protocol. [PDF]

BMJ Open
Milne-Ives M, Riccalton V, Plummer C, Threlfall L, Cong C, Ananthakrishnan A, Meinert E.   +6 more
europepmc   +1 more source

Pediatric Early Warning Score in interhospital ambulance care: a pilot study exploring feasibility and impact. [PDF]

Scand J Trauma Resusc Emerg Med
Luijmes M, Stevens J, Diets N, Tolsma R, de Groot J, Fuijkschot J.   +5 more
europepmc   +1 more source

Multicenter Development and Prospective Validation of eCARTv5: A Gradient-Boosted Machine-Learning Early Warning Score. [PDF]

Crit Care Explor
Churpek MM, Carey KA, Snyder A, Winslow CJ, Gilbert E, Shah NS, Patterson BW, Afshar M, Weiss A, Amin DN, Rhodes DJ, Edelson DP.   +11 more
europepmc   +1 more source

Early warning score and feasible complementary approach using artificial intelligence-based bio-signal monitoring system: a review. [PDF]

Biomed Eng Lett
Park D, So K, Prabhakar SK, Kim C, Lee JJ, Sohn JH, Kim JH, Lee SH, Won DO.   +8 more
europepmc   +1 more source

Correction: Early warning score validation methodologies and performance metrics: a systematic review. [PDF]

BMC Med Inform Decis Mak
Fang AHS, Lim WT, Balakrishnan T.
europepmc   +1 more source

Algorithm Refinement of the National Early Warning Score 2 (NEWS2): Study Protocol

Plummer C, Milne-Ives M, Cong C, Threlfall L, Meinert E.   +4 more
europepmc   +1 more source