Results 91 to 100 of about 6,056,797 (275)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Robust Lessons about Practical Early Warning Systems [PDF]
Early warning systems (EWSs) are subject to restrictions that apply to exchange rates in general: fundamentals matter but their influence is small and unstable.
Menkhoff, Lukas +2 more
core
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Early Warning System: Empirical Results from The Signals Approach [PDF]
The signals approach was applied to 24 of the indicators around the dates of the 29 banking and the 87 currency crises. In what follows, we first compare our results for the 15 original indicators in Kaminsky and Reinhart (1996) to those presented in ...
Kaminsky, Graciela +2 more
core
Explicit Modeling and Visualization of Imperfect Information in the Context of Decision Support for Tsunami Early Warning in Indonesia [PDF]
, 2011 A certainty model and appropriate visualization techniques are presented which are applied in a newly developed Decision Support System (DSS) for tsunami early warning deployed in Jakarta, Indonesia.
Raape, Ulrich +9 more
core +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
南方能源建设[Objective] This study addresses the issues of varying quality in safety risk early warning technologies for lithium battery energy storage stations and the conceptual confusion between "early warning" and "alarming." It aims to clarify the connotation ...
Liming WANG +6 more
doaj +1 more source
Towards a new model for early warning signals for systemic financial fragility and near crises: an application to OECD countries [PDF]
Using a signal extraction framework and looking at OECD countries over a 30 year period this paper attempts to identify a number of variables significant in predicting near-crises as a pre-cursor to full-fledged crises.
Clare, Andrew +2 more
core
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Modeling and detection of hydrodynamic trends for advancing early-tsunami warnings
, 2013 The automated detection of tsunamigenic signals at oceanic observation stations is highly desirable for the advancement of current tsunami early warning systems.
Lowe, Peter +9 more
core +1 more source