Results 241 to 250 of about 833,700 (304)

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Dengue epidemic alert thresholds for surveillance and decision-making in Puerto Rico: development and prospective application of an early warning system using routine surveillance data. [PDF]

BMJ Open
Thayer MB, Marzan-Rodriguez M, Torres Aponte J, Rivera A, Rodriguez DM, Madewell ZJ, Rysava K, Paz-Bailey G, Adams LE, Johansson MA.   +9 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Clinical evaluation of a machine learning-based early warning system for patient deterioration. [PDF]

CMAJ
Verma AA, Stukel TA, Colacci M, Bell S, Ailon J, Friedrich JO, Murray J, Kuzulugil S, Yang Z, Lee Y, Pou-Prom C, Mamdani M.   +11 more
europepmc   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Early warning system of the seasonal west nile virus infection risk in humans in northern greece, 2020-2024. [PDF]

Sci Rep
Angelou A, Pappa A, Markov PV, Gewehr S, Stilianakis NI, Kioutsioukis I.   +5 more
europepmc   +1 more source

Modified National Early Warning Score 2, a reliable early warning system for predicting treatment outcomes in patients with emphysematous pyelonephritis. [PDF]

World J Nephrol
Krishnamoorthy S, Thiruvengadam G, Sekar H, Palaniyandi V, Ramadurai S, Narayanasamy S.   +5 more
europepmc   +1 more source

Prospective external validation of a deep-learning-based early-warning system for major adverse events in general wards in South Korea. [PDF]

Acute Crit Care
Sim T, Cho EY, Kim JH, Lee KH, Kim KJ, Hahn S, Ha EY, Yun E, Kim IC, Park SH, Cho CH, Yu GI, Ahn BE, Jeong Y, Won JY, Cho H, Lee KB.   +16 more
europepmc   +1 more source

Real-world data-driven early warning system for risk-stratified liver injury in hospitalized COVID-19 patients-Machine learning models for clinical decision support. [PDF]

Front Public Health
Xiong Y, Cai X, Lai X, Wang Y, Xin H, Song W, Lv F, Guo X, Yang G, Wu Y.   +9 more
europepmc   +1 more source