Results 251 to 260 of about 168,289 (303)

Peri‐operative pain management in major lower extremity amputation in vascular Surgery: a UK anaesthetic and vascular surgery Delphi consensus study*

open access: yesAnaesthesia, EarlyView.
Summary Introduction Major lower extremity amputations occurring secondary to vascular disease remain prevalent worldwide. Pain surrounding these procedures is complex, multifactorial and associated with poor functional and psychosocial outcomes. The evidence base informing pain management approaches in major lower extremity amputations remain largely ...
Thanapon Ekkunagul   +81 more
wiley   +1 more source

Critical care delirium: prevention, identification and management: a narrative review

open access: yesAnaesthesia, EarlyView.
Summary Introduction Delirium is a frequent complication of critical illness and remains an important cause of short‐ and long‐term morbidity for patients admitted to ICUs. Delirium is associated with prolonged mechanical ventilation; extended ICU and hospital stay; and longer‐term health issues. Development is associated with patient (e.g.
Stephanie Kieswick, Ben Gibbison
wiley   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

open access: yesAndrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell   +3 more
wiley   +1 more source

Comparative Analysis of Pressure Drop (Δp): Hemodynamic Performance of Three Commercial Oxygenators During Cardiopulmonary Bypass

open access: yesArtificial Organs, EarlyView.
In this prospective study, a total of 60 patients were divided into three groups of 20 to compare the pressure drop (Δp) across three different oxygenators during cardiopulmonary bypass. The aim of this comparison was to enable evidence‐based optimization of the heart‐lung machine setup in order to minimize potential influencing factors and thereby ...
Jan Turra   +9 more
wiley   +1 more source

Outcomes in Patients Requiring VENO‐Venous Extracorporeal Membrane Oxygenation After Cardiac Surgery: An Analysis From the PELS‐1 Study

open access: yesArtificial Organs, EarlyView.
We report an insight from the PELS‐1– a multicentre, international registry focusing on postocardiotomy extracorporeal support use between 2000 and 2020. We focused on 24/2163 (1.1%) patients requiring V‐V ECMO after cardiac surgery. Mortality was high, with 21.7% of patients discharged alive and an overall 1‐year survival probability of 12.5 ...
Pasquale Nardelli   +39 more
wiley   +1 more source

Investigating relationships among strontium, barium, and seasonality in wild baboons

open access: yesArchaeometry, EarlyView.
Abstract Geochemical profiles of Australopithecus africanus and baboon teeth show fluctuating trace elements, possibly reflecting seasonal diets. Here we use laser ablation–inductively coupled plasma–mass spectrometric measurements of calcium‐normalized strontium and barium ratios (Sr/Ca and Ba/Ca) and ion microprobe analyses of oxygen isotopes (δ18O ...
Maya Bharatiya   +12 more
wiley   +1 more source

Trace Element Patterns in Juvenile Wild Chimpanzee Dentitions

open access: yesArchaeometry, EarlyView.
ABSTRACT Trace elements are used to infer mammalian early‐life diets, environmental toxins, dispersal patterns, stress histories, and weaning ages. Here, we employ laser ablation‐inductively coupled plasma‐mass spectrometry (LA‐ICP‐MS) to reveal elemental patterns in our closest living relatives, chimpanzees.
Tanya M. Smith   +5 more
wiley   +1 more source

A multicentre analysis of efficacy, safety and molecular response correlates of fostamatinib in warm autoimmune haemolytic anaemia and Evans syndrome

open access: yesBritish Journal of Haematology, EarlyView.
Fostamatinib had 46% durable response, with 73% steroid reduction, in this multicentre retrospective study of refractory wAIHA/ES. Hypertension, gastrointestinal (GI) distress and neutropenia occurred in 23%. Only one patient required drug discontinuation and one patient dose reduction.
Jorge N. Ruiz Lopez   +16 more
wiley   +1 more source

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