Results 131 to 140 of about 3,391,934 (334)

Alien Invaders! On-Site Programming (Grade 6)

open access: yes, 2008
In the “Alien Invaders!” program, students investigate how quagga mussels might affect Lake Mead. Students collect water quality data such as clarity, pH, and temperature to determine current habitat conditions that have allowed quagga mussels to thrive ...
Discover Mojave: Forever Earth
core  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Earth [PDF]

open access: yes
This lithograph depicts a view of Earth taken from Apollo 10 during its journey to the Moon in May 1969. False-color satellite images showing chlorophyll concentration, sea surface temperature, topography, and ozone concentration are also featured.

core  

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

CONTRIBUTIONS REGARDING THE IMPROVEMENT OF SPECIFIC PHYSICAL TRENING ON LAND OF ALPINE SKIERS [PDF]

open access: yesAnnals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2019
This work is designed to complement the shortcomings created in the preparation of alpine skiers in relation to technological development and the development of alpine skiing internationally.
Grosu Bogdan-Marius, Stoleru Răzvan
doaj  

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

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