Results 161 to 170 of about 1,162,220 (312)

The Unconscious and the Island: Fragments of Research on the Self

open access: yesNordicum-Mediterraneum, 2015
A brief exploration of volcanic and other Nordic-Mediterranean archetypes according to Jungian ...
Roberto Buccola
doaj  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Earth & Sky Podcasts

open access: yes
Users can subscribe to this free service, which will automatically send a new podcast each day. Topics include nanotechnology, astrophysics and space, observing Earth, and the human world.

core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Nebeská sféra v Parmenidově kosmologii

open access: yesFilosofický časopis
The influence of Parmenides’ thinking is to be seen especially in the field of ontology. This is not so much the case in the field of cosmology, although its concomitant could be the concept of the celestial sphere, which for Aristotle enclosed the ...
Kočandrle, Radim
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Earth tides, earthquake occurrence and earth deformation

open access: yes, 2010
An analysis of Earth deformation, earthquakes and tides has been undertakenusing Earth tide and interferometric SAR data from ESA satellites. The abilityof Earth tides to trigger earthquakes has been investigated by measuring thestatistical relationship ...
Kansowa, Tarek
core  

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