Results 111 to 120 of about 178,779 (300)

Spatial modeling in GIS and R for earth and environmental sciences / [PDF]

"Spatial Modeling in GIS and R for Earth and Environmental Sciences offers an integrated approach to spatial modelling using both GIS and R. Given the importance of Geographical Information Systems and geostatistics across a variety of applications in ...
Pourghasemi, Hamid Reza,editor., Gokceoglu, Candan,editor.   +1 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Explaining international co-authorship in global environmental change research [PDF]

This paper maps the domain of earth and environmental sciences (EES) and investigates the relationship between cognitive problem structures and internationalisation patterns, drawing on the concepts of systemic versus cumulative global environmental ...
Jappe-Heinze, Arlette
core  

Responses to environmental and societal challenges for our unstable earth (RESCUE), ESF Forward Look – ESF-COST ‘Frontier of Science’ joint initiative [PDF]

, 2011
RESCUE, an ESF-COST ‘Frontier of Science’ initiative and an ESF Forward Look, is highly integrative, and is supported by 8 Committees of ESF and COST, namely the ESF Standing Committees for Life, Earth and Environmental Sciences (LESC), for Social ...
Goodsite, Michael, Avril, Bernard, O’Brien, Karen, Jäger, Jill, Pálsson, Gísli, Hordijk, Leen, European Cooperation in Science and Technology, European Science Foundation, Pahl-Wostl, Claudia   +8 more
core  

On the foundations of Earth foundation models

Communications Earth & Environment
Foundation models have enormous potential in advancing Earth sciences. However, current approaches may not be optimal, as they focus only on a few basic features of a desirable Earth foundation model.
Xiao Xiang Zhu, Zhitong Xiong, Yi Wang, Adam J. Stewart, Konrad Heidler, Yuanyuan Wang, Zhenghang Yuan, Thomas Dujardin, Qingsong Xu, Yilei Shi   +9 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

A concept for seabed rare earth mining in the eastern South Pacific [PDF]

, 2012
This report presents a concept for mining of rare earth elements from seabed sediment in a promising area of the eastern South Pacific. The document begins with an introduction to the seabed, its regulation and resources.
Bashir, M.B., Zhang, W, Kiosidou, E., Kim, S.H., Wolgamot, H.   +4 more
core