Results 121 to 130 of about 1,042,122 (308)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Lunar power system summary of studies for the lunar enterprise task force NASA-office of exploration [PDF]

open access: yes
The capacity of global power systems must be increased by a factor of ten to provide the predicted power needs of electric power by the year 2050. The Lunar Power System (LPS) would collect solar energy at power bases located on opposing limbs of the ...
Criswell, David R.
core   +1 more source

Recycling of textile waste by reinforcing earthy render with micro-fiber [PDF]

open access: yes, 2013
Earth construction is worldwide spread. It is a valuable heritage to preserve because of its cultural and socio-economical relevance. Furthermore, earth construction, since it needs significantly less energy than modern construction techniques, and ...
Caldeira, F.   +4 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Earth construction: bird teaching [PDF]

open access: yes, 2009
The paradigm of earth being a traditional and a modern building material has been related to the fact that it is natural, ecological, recycled, abundant and economic.
Correia, J.   +5 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The effects of climatic conditions on attitudinal changes towards earth construction in South Africa

open access: yesActa Structilia, 2014
Earth construction is an appropriate method for building houses in arid and semi-arid areas in South Africa due to its low environmental impact and responsible use of on-site resources.
Gerhard Bosman, Diaan van der Westhuizen
doaj  

Neutrinos and (Anti)neutrinos from Supernovae and from the Earth in the Borexino detector

open access: yes, 2003
The main goal of the Borexino detector, in its final phase of construction in the Gran Sasso underground laboratory, is the direct observation and measurement of the low energy component of neutrinos coming from the Sun. The unique low energy sensitivity
Miramonti, Lino
core  

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