Results 51 to 60 of about 1,562 (268)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A Probabilistic Weighted Archetypal Analysis Method with Earth Mover’s Distance for Endmember Extraction from Hyperspectral Imagery

open access: yesRemote Sensing, 2017
A Probabilistic Weighted Archetypal Analysis method with Earth Mover’s Distance (PWAA-EMD) is proposed to extract endmembers from hyperspectral imagery (HSI).
Weiwei Sun   +5 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Inferring phenotypic properties from single-cell characteristics. [PDF]

open access: yesPLoS ONE, 2012
Flow cytometry provides multi-dimensional data at the single-cell level. Such data contain information about the cellular heterogeneity of bulk samples, making it possible to correlate single-cell features with phenotypic properties of bulk tissues ...
Peng Qiu
doaj   +1 more source

GazeEMD: Detecting Visual Intention in Gaze-Based Human-Robot Interaction

open access: yesRobotics, 2021
In gaze-based Human-Robot Interaction (HRI), it is important to determine human visual intention for interacting with robots. One typical HRI interaction scenario is that a human selects an object by gaze and a robotic manipulator will pick up the object.
Lei Shi, Cosmin Copot, Steve Vanlanduit
doaj   +1 more source

RBIR Based on Signature Graph

open access: yes, 2015
This paper approaches the image retrieval system on the base of visual features local region RBIR (region-based image retrieval). First of all, the paper presents a method for extracting the interest points based on Harris-Laplace to create the feature ...
Le, Thanh Manh, Van, Thanh The
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Tensor-SIFT Based Earth Mover’s Distance for Contour Tracking [PDF]

open access: yesJournal of Mathematical Imaging and Vision, 2012
28 pages, 9 figures, 2 ...
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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