Results 61 to 70 of about 29,046,416 (302)
Thalia: a global, multi-modal dataset for volcanic activity monitoring
Machine Learning. EarthMonitoring volcanic activity is of paramount importance to safeguarding lives, infrastructure, and ecosystems. However, only a small fraction of known volcanoes are continuously monitored.
Nikolas Papadopoulos +5 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Quantitative modelling of the human–Earth System a new kind of science?
, 2013 The five grand challenges set out for Earth System Science by the International Council for Science in 2010 require a true fusion of social science, economics and natural science—a fusion that has not yet been achieved.
Finnigan, John +2 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Half-title page: Teaching earth science in the junior high school
, 1966 This teaching guide consists of unit plans for the various divisions of earth science. The plans are, as the title suggests, a guide for the teacher and could be used In conjunction with any number of earth science textbooks; the writer has elected to ...
Regnier, Patricia, 1943-
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Maǧallaẗ Markaz Al-Buḥūṯ Al-Ǧuġrāfiyyaẗ wa Al-Kārtūğirāfiyyaẗ, 2003 Edward Tarbuck +2 more
doaj +1 more source
Lead Isotope Ratio Optimization using Q-ICP-MS for Volcanic Rocks
Jurnal Kimia Sains dan AplikasiLead isotope ratios are a valuable tool for tracing the origin and evolution of volcanic rocks, supporting exploration of critical metals for renewable energy. While multi-collector and thermal ionization mass spectrometers offer superior precision, they
Mutiara Effendi +2 more
doaj +1 more source