Results 111 to 120 of about 1,474,341 (311)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Opportunities and challenges for people-centered multi-hazard early warning systems: Perspectives from the Global South

iScience
Summary: This perspective critically examines the challenges and opportunities of implementing people-centered multi-hazard early warning systems (MHEWS) in the Global South.
Budimir Mirianna, Šakić Trogrlić Robert, Almeida Cinthia, Arestegui Miguel, Chuquisengo Vásquez Orlando, Cisneros Abel, Cuba Iriarte Monica, Dia Adama, Lizon Leon, Madueño Giorgio, Ndiaye Alioune, Ordoñez Caldas Miluska, Rahman Tamanna, RanaTharu Bikram, Sall Alpha, Uprety Dharam, Anderson Chris, McQuistan Colin   +17 more
doaj   +1 more source

At last : intelligent publishing! [PDF]

, 2012
Scientific publishing was simpler when we only had paper to use. In the Earth sciences, for example, we had printed maps, books, reports, pamphlets and journal papers, all very familiar to publishers and readers.
Westhead, Keith
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

From multi-hazard early warning systems (MHEWS) to all-vulnerability warning systems (AVWS)

iScience
Summary: Science, policy, and practice have long accepted that disasters occur due to vulnerabilities rather than hazards, yet approaches to warnings still tend to be hazard-focused.
Ilan Kelman, Carina J. Fearnley
doaj   +1 more source

Earth observations from space: Outlook for the geological sciences [PDF]

Remote sensing from space platforms is discussed as another tool available to geologists. The results of Nimbus observations, the ERTS program, and Skylab EREP are reviewed, and a multidisciplinary approach is recommended for meeting the challenges of ...
Lowman, P. D., Jr., Short, N. M.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Use of Mohr diagrams to predict fracturing in rock masses, with applications for predicting sub-surface behavior

iScience
Summary: Mohr diagrams are a simple and effective method that can help geoscientists consider, model, and predict the ranges of mechanical properties of rock, stresses, fluid pressures, and the resultant fractures that are likely to occur in the sub ...
D.C.P. Peacock, David J. Sanderson, Bernd Leiss   +2 more
doaj   +1 more source