Results 111 to 120 of about 1,481,460 (305)

Opportunities and challenges for people-centered multi-hazard early warning systems: Perspectives from the Global South

iScience
Summary: This perspective critically examines the challenges and opportunities of implementing people-centered multi-hazard early warning systems (MHEWS) in the Global South.
Budimir Mirianna, Šakić Trogrlić Robert, Almeida Cinthia, Arestegui Miguel, Chuquisengo Vásquez Orlando, Cisneros Abel, Cuba Iriarte Monica, Dia Adama, Lizon Leon, Madueño Giorgio, Ndiaye Alioune, Ordoñez Caldas Miluska, Rahman Tamanna, RanaTharu Bikram, Sall Alpha, Uprety Dharam, Anderson Chris, McQuistan Colin   +17 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Does democratic backsliding undermine climate policy? No evidence (yet)

iScience
Summary: Countries with liberal democratic institutions tend to have stricter climate policies and have made more progress in reducing emissions than autocracies.
Thomas Bernauer, Tobias Böhmelt
doaj   +1 more source

Applications of ISES for vegetation and land use [PDF]

Remote sensing relative to applications involving vegetation cover and land use is reviewed to consider the potential benefits to the Earth Observing System (Eos) of a proposed Information Sciences Experiment System (ISES).
Wilson, R. Gale
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Measuring environmental (in)justices: Insights from a systematic literature review on methodological approaches

iScience
Summary: Environmental (in)justice research uses various conceptual frameworks and methodological approaches, leading to fragmentation across contexts and disciplines.
Jacqueline Loos, Charlotte Gohr, Noelia Zafra-Calvo, Gonzalo Cortés-Capano, Anna Lena Tonninger, Henrik von Wehrden   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Amendment of saline-alkali soils promotes the formation and stability of iron-bound organic carbon

iScience
Summary: Iron oxides protect soil organic carbon (SOC) over the long term, but the effects of saline-alkali soil amendments on iron-bound organic carbon (Fe-OC) remain unclear.
Shuhan Wang, Xueqin Ren, Tairan Zhou, Yun Zhang, Shuwen Hu, Biao Zhu   +5 more
doaj   +1 more source

SR-FTiR microscopy and FTIR imaging in the earth sciences

, 2013
During the last decades, several books have been devoted to the application of spectroscopic methods in mineralogy. Several short courses and meetings have addressed particular aspects of spectroscopy, such as the analysis of hydrous components in ...
Bellatreccia, F., Della Ventura, G., Marcelli, A.   +2 more
core   +1 more source

The earth science and nonlinear science

Chinese Science Bulletin, 1998
Liu, Shida, Liu, Shikuo
openaire   +1 more source