Results 111 to 120 of about 11,427,892 (265)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
NATURAL HAZARDS AND EARTH SYSTEM SCIENCES (ISSN: 1561-8633)
Natural Hazards and Earth System Sciences (NHESS) is an interdisciplinary and international journal dedicated to the public discussion and open-access publication of high-quality studies and original research on natural hazards and their consequences ...
PINARDI, NADIA
core
Topographic reconstruction from radar imagery [PDF]
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1988.Includes bibliographical references.by Joseph R.
Matarese, Joseph R. (Joseph Richard)
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Summary: This perspective critically examines the challenges and opportunities of implementing people-centered multi-hazard early warning systems (MHEWS) in the Global South.
Budimir Mirianna +17 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Optical investigation of cometary nuclei [PDF]
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept.
Meech, Karen Jean
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Does democratic backsliding undermine climate policy? No evidence (yet)
Summary: Countries with liberal democratic institutions tend to have stricter climate policies and have made more progress in reducing emissions than autocracies.
Thomas Bernauer, Tobias Böhmelt
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The structure and thermal tectonics of planetary lithospheres : mid-ocean ridges and lunar impact basins [PDF]
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1985.Vita.Includes bibliographies.by Steven Richard Bratt.Ph ...
Bratt, Steven Richard
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Summary: Environmental (in)justice research uses various conceptual frameworks and methodological approaches, leading to fragmentation across contexts and disciplines.
Jacqueline Loos +5 more
doaj +1 more source

