Results 31 to 40 of about 1,466,569 (295)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
STAR ProtocolsSummary: Unmanned aerial vehicle (UAV) or drone image data are useful tools for creating machine learning-based mangrove categorization maps. Here, we present a protocol for creating a taxonomy map of mangrove species using machine learning and ...
Dung Trung Ngo +3 more
doaj +1 more source
The challenges of dynamic vulnerability and how to assess it
iScience, 2022 Summary: Recent disasters have demonstrated the challenges faced by society as a result of the increasing complexity of disaster risk. In this perspective article, we discuss the complex interactions between hazards and vulnerability and suggest ...
Marleen C. de Ruiter, Anne F. van Loon
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
STAR ProtocolsSummary: Organochlorides are a crucial class of electrophiles in organic synthesis. Here, we present a protocol for the cross-electrophile coupling of aryl chlorides with unactivated alkyl chlorides, facilitated by an iron/B2pin2 catalytic system.
Pengjie Xian +4 more
doaj +1 more source
, 2007 New Theory of the Earth is an interdisciplinary advanced textbook on all aspects of the interior of the Earth and its origin, composition, and evolution: geophysics, geochemistry, dynamics, convection, mineralogy, volcanism, energetics and thermal ...
Anderson, Don L.
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Enhanced global extreme droughts driven by the Indian Ocean and Pacific Ocean on decadal timescales
iScienceSummary: In the 21st century, two record-breaking years of extreme drought coverage swept across the globe. These resulted in billions of agriculture losses and led to hunger and poverty in those developing countries.
Yihui Xu +4 more
doaj +1 more source
Heliyon, 2016 In 1891 a report was published by an ASCE committee to investigate the cause of the Johnstown flood of 1889. They concluded that changes made to the dam by the South Fork Fishing and Hunting Club did not cause the disaster because the embankment would ...
Neil M. Coleman +2 more
doaj +1 more source
Virginia Earth Science Collaborative: Developing Highly Qualified Earth Science Teachers [PDF]
, 2008 A collaborative of seven institutes of higher education and two non-profit organizations developed and implemented five earth science courses totaling eighteen credits that enabled secondary teachers to acquire an add-on earth science endorsement: Geology ...
Cothron, J.
core +1 more source