Results 41 to 50 of about 1,116 (301)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Safety assessment of high voltage substation earthing systems with synthetic geotextile membrane
Journal of Mechatronics, Electrical Power, and Vehicular Technology, 2019 High voltage substations built within areas prone to vegetation or with unfavourable subgrade conditions are paved with the addition of punched geotextiles and non-conductive synthetic fabrics underneath switchyard surfacing.
Mostafa Nazih
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Incomplete Cross-Bonding in the MV Line. Experience from the Operation of MV Single Cable Lines
Energies, 2020 Cable lines are one of the basic components of power systems. Medium and high voltage cables mainly comprise a metallic sheath, which is concentric to the main core conductor.
Krzysztof Dobrzynski +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Solar Energy AdvancesPhotovoltaic (PV) systems play a pivotal role in addressing the growing global demand for sustainable and renewable energy sources, offering a crucial solution to mitigate climate change and reduce dependence on fossil fuels. Due to outdoor installation,
Mohammad Parhamfar +2 more
doaj +1 more source
Performance of Practical Grounding Systems under High Impulse Conditions
Energies, 2018 This paper investigates the factors affecting the impulse characteristics of purposely built grounding systems. We installed 2 m × 2 m grounding systems in four different sites with different soil resistivity values.
Muhd Shahirad Reffin +3 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Advanced Diagnostic Techniques for Earthing Brush Faults Detection in Large Turbine Generators
EnergiesLarge steam turbine generators are increasingly vulnerable to damage from shaft voltages and bearing currents due to the widespread adoption of modern power electronic excitation systems and more flexible operating regimes.
Katudi Oupa Mailula, Akshay Kumar Saha
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source