Results 71 to 80 of about 282,797 (297)

Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA

Advanced Science, EarlyView.
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang, Yunyun An, Mengqi Yang, Yuqi Pan, Xiaoyi Liu, Fanglei Gong, Huizhen Lin, Bianbian Tang, Yunxia Bai, Xin Zhao, Yu Zhao, Changzheng Du, Kun Sun   +12 more
wiley   +1 more source

Open access tools for quality-assured and efficient data entry in a large, state-wide tobacco survey in India

Global Health Action, 2017
Background: A large state-wide tobacco survey was conducted using modified version of pretested, globally validated Global Adult Tobacco Survey (GATS) questionnaire in 2015–22016 in Tamil Nadu, India.
Hemant Deepak Shewade, E Vidhubala, Divyaraj Prabhakar Subramani, Pranay Lal, Neelam Bhatt, C. Sundaramoorthi, Rana J. Singh, Ajay M. V. Kumar   +7 more
doaj   +1 more source

A history of East Asia: from the origins of civilization to the twenty-first century [PDF]

, 2011
Charles Holcombe, NC DOCKS at The University of North Carolina at Greensboro   +1 more
openalex   +1 more source

Carrier frequency and incidence estimation of Smith–Lemli–Opitz syndrome in East Asian populations by Genome Aggregation Database (gnomAD) based analysis [PDF]

, 2021
Jong Eun Park, Taeheon Lee, Kyeongsu Ha, Chang‐Seok Ki   +3 more
openalex   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

Genome-wide survey indicates diverse physiological roles of the barley (Hordeum vulgare L.) calcium-dependent protein kinase genes

Scientific Reports, 2017
Calcium-dependent protein kinases (CDPKs) are crucial calcium sensors that play important roles in the regulation of plant growth and developmental processes, as well as protective responses to environmental stress. Here, we identified 28 CDPK genes from
Yunqiang Yang, Qiuli Wang, Qian Chen, Xin Yin, Min Qian, Xudong Sun, Yongping Yang   +6 more
doaj   +1 more source

Urogynaecology Training in South East Asia (SEA) and Asia

Majalah Obstetri dan Ginekologi, 2019
South East Asia (SEA) is made up of 11 countries (Viet-nam, Laos, Cambodia, Thailand, Myanmar, Malaysia, Singapore, Brunei, Philippines, Indonesia and Timor Leste) from Myanmar in the northwest to Timor Leste in the far south east.
Ng Kwok Weng Roy
doaj   +1 more source

Modern and Ancient Genomes Reveal Neolithic Paternal Expansions of Millet and Rice Farmers and Demic Diffusion from China into Mainland Southeast Asia

Advanced Science, EarlyView.
This study clarifies the genetic patterns of paternal lineages across East Asia and Mainland Southeast Asia. Han populations are relatively homogeneous, whereas southern ethnolinguistic minorities display regional structures. Shared Y‐chromosome lineages indicate Neolithic expansions and extensive north‐south gene flow, supporting demic diffusion ...
Yunhui Liu, Lintao Luo, Yutong Jiang, Minzhu Zhao, Ting Yang, Zhiyong Wang, Lisiteng Luo, Yuhang Feng, Zihao Zhu, Yuzhu Wang, Limei Zhang, Bofeng Zhu, Chao Liu, Renkuan Tang, Mengge Wang, Guanglin He   +15 more
wiley   +1 more source

The United States’ Strategic Interests: The Centrality of East Asia, the Importance of the Pivot and the Risk of Distraction

Malaysian Journal of International Relations, 2015
The article examines the strategic dilemma faced by the United States (U.S.) concerning the conflicting interests in the Middle East and East Asia. The article focuses on analysing U.S. policy towards East Asia within the context of Obama’s Pivot to Asia
Balazs Szanto
doaj   +1 more source

Biodiversity and ecosystem services: Towards ecological security in trop-ical and subtropical East Asia [PDF]

, 2018
Richard T. Corlett
openalex   +1 more source