Results 31 to 40 of about 1,250,446 (353)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Alienation and authoritarian appropriation – the spatiotemporality of political subjectivation under East German urban neoliberalism

Zeitschrift für Rechtsextremismusforschung
This paper contributes to a growing field of spatial analyses of authoritarianism by asking how urban neoliberalization impacts authoritarian subjectivation.
Leon Rosa Reichle
doaj   +1 more source

The costs of remoteness: evidence from German division and reunification [PDF]

, 2004
This paper exploits the division of Germany after the Second World War and the reunification of East and West Germany in 1990 as a natural experiment to provide evidence of the importance of market access for economic development. In line with a standard
Redding, Stephen, Sturm, Daniel M.
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Trends in Women’s Educational Advantage and Divorce in East and West Germany

Comparative Population Studies
Couples in which wives have more education than their husbands have been found to be more likely than other couples to divorce. But this relationship varies across time and place.
Flavia Mazzeo, Christine Schwartz, Stefani Scherer, Agnese Vitali   +3 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The association of public health interventions regarding both infant sleep position and pertussis immunization with sudden infant death syndrome rates: an ecological study

BMC Pediatrics
Background Infections may play a role in the etiology of sudden infant death syndrome (SIDS), with Bordetella pertussis being a potential agent. The objective was to analyze the association of SIDS and infant pertussis hospitalization rates over time ...
Jacqueline Müller-Nordhorn, Amir Hakimhashemi, Stefan N. Willich, Sylvia Binting, Thomas Keil   +4 more
doaj   +1 more source

Budgets of atmospheric sulfur for East Germany based on meso-α-scale simulations

Meteorologische Zeitschrift, 1996
Two SANA special observation episodes have been simulated with the EURAD model. The first one (called SANA­A) extends from 10 to 20 October 1990 and the second episode (SANA-B) extends from 28 August to 6 September 1991.
Hendrik Feldmann, Heinz Hass, Michael Memmesheimer, Hermann J. Jakobs   +3 more
doaj   +1 more source

East Germany Yesterday and Tomorrow

Wirtschaftsdienst, 2021
In November 2019, Germany celebrated 30 years since the fall of the Berlin Wall. But the mood today is gloomy. Two-thirds of East Germans consider themselves second-class citizens, according to a survey by the Allensbach Institute for Public Opinion ...
Dalia Marin
doaj   +1 more source