Results 111 to 120 of about 459,162 (303)

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Millimeter‐level precision in a seafloor geodesy experiment at the Discovery transform fault, East Pacific Rise

Geochemistry, Geophysics, Geosystems, 2013
Direct‐path acoustic ranging is a promising seafloor geodetic technique for continuous high‐resolution monitoring of geodynamical process such as fault slip and magma intrusion.
Jeffrey J. McGuire, John A. Collins
doaj   +1 more source

Insights into dike nucleation and eruption dynamics from high-resolution seismic imaging of magmatic system at the East Pacific Rise. [PDF]

Sci Adv, 2023
Marjanović M, Carbotte SM, Stopin A, Singh SC, Plessix RÉ, Marjanović M, Nedimović MR, Canales JP, Carton HD, Mutter JC, Escartín J.   +10 more
europepmc   +1 more source

Opioid Toxicity Following Concomitant Use of Macrolide Antibiotics with Fentanyl, Hydromorphone, or Oxycodone: A Population‐Based Study

Clinical Pharmacology &Therapeutics, EarlyView.
Fentanyl, hydromorphone, and oxycodone are metabolized by cytochrome P450 3A4 (CYP3A4). Co‐administration with CYP3A4‐inhibiting macrolides (clarithromycin or erythromycin) may increase opioid concentrations and overdose risk, but the clinical impact of these interactions is unknown.
Tony Antoniou, Joanna Yang, David N. Juurlink, Joanne M.‐W. Ho, Muhammad Mamdani, Fangyun Wu, Mina Tadrous, Tara Gomes   +7 more
wiley   +1 more source

Surprising discovery of off-axis hydrothermal venting on the East Pacific Rise. [PDF]

Proc Natl Acad Sci U S A, 2022
Seyfried WE, Karson JA.
europepmc   +1 more source

A comparative analysis of the emphases in world history textbooks and articles in the American Historical Review [PDF]

, 1952
Thesis (Ed.M.)--Boston UniversityThe purpose of this study is to examine current world history textbooks to distinguish the points of emphasis, to examine the leading articles in professional historical publications to ascertain what broad areas have ...
Vitale, Francis R.
core   +1 more source

Drug Critical Limits for Urgent Physician Notification

Clinical Pharmacology &Therapeutics, EarlyView.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang, Yasmeen Ibrahim, Kyle Cheng, Gerald J. Kost   +3 more
wiley   +1 more source

A regulatory hydrogenase gene cluster observed in the thioautotrophic symbiont of Bathymodiolus mussel in the East Pacific Rise. [PDF]

Sci Rep, 2022
Patra AK, Perez M, Jang SJ, Won YJ.
europepmc   +1 more source

Defining Reconciliation Studies: Theoretical and Practical Dimensions

Conflict Resolution Quarterly, EarlyView.
ABSTRACT Reconciliation studies (RS) has become increasingly influential in understanding alternative views to ending conflict and dealing with the aftermath. As a discipline or field, however, it is not well defined. The actual usefulness of reconciliation (as a concept), or of RS (as a discipline), is debated, and due to its growing usage, it is ...
Colleen Alena O’Brien
wiley   +1 more source

Discovery of active off-axis hydrothermal vents at 9° 54'N East Pacific Rise. [PDF]

Proc Natl Acad Sci U S A, 2022
McDermott JM, Parnell-Turner R, Barreyre T, Herrera S, Downing CC, Pittoors NC, Pehr K, Vohsen SA, Dowd WS, Wu JN, Marjanović M, Fornari DJ.   +11 more
europepmc   +1 more source