Results 51 to 60 of about 497,142 (327)

Subparallel thrust and normal faulting in Albania and the roles of gravitational potential energy and rheology contrasts in mountain belts [PDF]

, 2009
The active tectonics of Albania and surrounding regions, on the eastern margin of the Adriatic Sea, is characterized by subparallel thrust and normal faulting which, we suggest, is likely to be related to gravitational potential energy contrasts between ...
Boait, Fran, Copley, Alex, Hollingsworth, James, Jackson, James, McKenzie, Dan   +4 more
core   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Mediterranean Sea response to climate change in an ensemble of twenty first century scenarios [PDF]

, 2015
The Mediterranean climate is expected to become warmer and drier during the twenty-first century. Mediterranean Sea response to climate change could be modulated by the choice of the socio-economic scenario as well as the choice of the boundary ...
A Arakawa, A Carillo, A Harzallah, A Lascaratos, A Lascaratos, A Mariotti, A Theocharis, AL Gibelin, B Ingleby, B Klein, C Dubois, C Naranjo, Clotilde Dubois, D Pettenuzzo, Damià Gomis, E Sanchez-Gomez, E Sanchez-Gomez, EJ Rohling, EJ Rohling, Elena Padorno, Enrique Alvarez-Fanjul, EV Stanev, F Giorgi, Fanny Adloff, Florence Sevault, G Sannino, Gabriel Jordà, J Beuvier, J Soto-Navarro, JF Royer, JH Christensen, L Li, L Li, M Déqué, M Déqué, M Déqué, M Herrmann, M Herrmann, M Herrmann, M Herrmann, M Marcos, M Tsimplis, Marine Herrmann, Marta Marcos, Michel Déqué, MV Struglia, N Elguindi, N Skliris, N Skliris, P Oddo, PG Myers, RB Thorpe, Roland Aznar, S Gualdi, S Marullo, S Matthiesen, S Planton, S Somot, S Valcke, Samuel Somot, SM Uppala, V Zervakis, VH Kourafalou, W Ludwig, W Roether, W Roether   +65 more
core   +3 more sources

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Elemental Analysis and Mapping of Some Natural Waters in Eastern Black Sea Region and Investigation of Their Effects on Environment and Human Health

Doğal Afetler ve Çevre Dergisi, 2017
In this study, it was aimed to make an elemental analysis of the natural spring waters in 7 cities (Artvin, Rize, Trabzon, Giresun, Ordu, Gümüşhane and Bayburt) in the Eastern Black Sea region and to determine the elemental distribution of the entire ...
Yaşar Kobya, Cafer Mert Yeşilkanat
doaj   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

Determination of Sulphurdioxide (SO2) Distribution in the Eastern Black Sea Region with Geographical Information System

Doğal Afetler ve Çevre Dergisi, 2016
Air pollution occurs more particularly in areas where there are an intense and unplanned urbanization. Because of the pollution, air quality is reduced and the pollution causes the various health problems.
Kazım Onur Demirarslan, Halil Akıncı
doaj   +1 more source

Unsupervised Hierarchical Symbolic Regression for Interpretable Property Modeling in Complex Multi‐Variable Systems

Advanced Science, EarlyView.
UHSR translates complex chemical behavior into clear and explainable equations. Applied to thin‐layer chromatography, it automatically uncovers the mathematical rules linking a molecule's structure to its polarity. This approach matches the accuracy of advanced AI while providing interpretable results, earning greater trust from chemists. The method is
Siyu Lou, Chengchun Liu, Dongxiao Zhang, Yuntian Chen, Fanyang Mo   +4 more
wiley   +1 more source

Sinop Müzesi’nden Bir Grup Roma Amphorası Üzerinden MÖ 1. Yüzyıl - MS 7. Yüzyıl Arası Karadeniz Ticaretine Genel Bir Bakış / A General Overview of the Black Sea Trade between the 1st Century BC and the 7th Century AD through a Group of Roman Amphoras from the Sinop Museum

Arkhaia Anatolika
This article aims to evaluate the commercial interaction of the Black Sea region through the distribution of amphorae by typological study of imported amphoras dating back to the Roman imperial period.
Billur TEKKÖK-KARAÖZ , Babür Mehmet AKARSU, Deniz TAMER, Ebru TAMER   +3 more
doaj   +1 more source

Geothermal field of the transition area between the Anatolian Plate and the East European Platform

Журнал Белорусского государственного университета: География, геология, 2019
Heat flow data from the Eastern Mediterranean region indicates an extensive province of low heat flow, spreading over the whole basin of the Mediterranean to the east of Crete (Levantine Sea), Cyprus, and Northern Egypt.
Siamak Mansouri Far
doaj   +1 more source