Results 91 to 100 of about 163,226 (230)

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

British Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang, Chen‐Han Chueh, Chien‐Yu Tseng, Christopher N. Kaufmann, Earl J. Morris, Chiao‐En Wu, Yi‐Wen Tsai   +6 more
wiley   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer

British Journal of Clinical Pharmacology, EarlyView.
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog, Niven Mehra, Anouk van Kleef, Diederik M. Somford, Inge M. van Oort, Alex L. T. Imholz, Paul Hamberg, Nielka P. van Erp, Emmy Boerrigter   +8 more
wiley   +1 more source

Area Studies and Eastern Europe: How Eastern Europe Collapsed

Anali Hrvatskog Politološkog Društva, 2007
In the first part, the author outlines the development of area studies in contemporary comparative politics, and points to their importance for the development of political science.
Mirjana Kasapović
doaj  

Prescribing variation across Europe: Insights into prescribing practices and educational needs

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing medication is a complex process, influenced by many factors that can be weighed differently. Four prescriber profiles have been identified: pragmatic‐contextual, guideline‐oriented, experience‐driven and vulnerability‐focused. However, the extent to which European prescribers identify with these profiles and the role of these profiles ...
Mariëlle G. Hartjes, Milan C. Richir, Michiel A. van Agtmael, Jelle Tichelaar   +3 more
wiley   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

How can welfare regime and production regime theories explain differences in schools’ ability grouping policies? A comparative study using the PISA school survey

British Educational Research Journal, EarlyView.
Abstract Research evidence is mixed on the consequences of ability grouping policies, but most research has found an overrepresentation of disadvantaged social demographics in low‐ability groups. However, researchers have neglected to explain why ability grouping policies vary between countries.
Monica Reichenberg, Girma Berhanu, Lena Fridlund   +2 more
wiley   +1 more source

System failure? Exploring the interplay of fear of failure, competition, cooperation and sense of belonging in education in England and Flanders

British Educational Research Journal, EarlyView.
Abstract Fear of failure is damaging in a host of ways yet is rife in many schools. Drawing on self‐worth theory, we explore whether fear of academic failure is higher in education systems with features that increase students' experiences of competition. To do this, we compare two very different education systems: England, where, for instance, national
Carolyn Jackson, Mieke Van Houtte
wiley   +1 more source

Trade of Lithuanian Dairy Products and Vertical Relationship at the Stage of Distribution

Ekonomika, 2002
This paper focuses on the theory of vertical co-ordination and its application to agriculture and the dairy industry. More specially, the paper analyses the distribution of Lithuanian dairy products in both the domestic and international market.
Heinrich Hockmann, Angelė Kėdaitienė
doaj