Results 111 to 120 of about 7,003,105 (359)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Easy Language in Italy

open access: yes, 2021
This is a chapter is about both the past and the present of Easy Italian in the European context. It takes its reader on a tour of Italy, opening windows and peeking into dif¬ferent aspects of the way Easy Italian has been (or has not been) implemented in diverse sectors, and reveals how Easy Language and accessible communication are realized in a wide
openaire   +1 more source

Programming language semantics: It’s easy as 1,2,3

open access: yesJournal of Functional Programming, 2023
Abstract Programming language semantics is an important topic in theoretical computer science, but one that beginners often find challenging. This article provides a tutorial introduction to the subject, in which the language of integers and addition is used as a minimal setting in which to present a range of semantic concepts in simple manner.
openaire   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Is less readable liked better? The case of font readability in poetry appreciation.

open access: yesPLoS ONE, 2019
Previous research shows conflicting findings for the effect of font readability on comprehension and memory for language. It has been found that-perhaps counterintuitively-a hard to read font can be beneficial for language comprehension, especially for ...
Xin Gao   +3 more
doaj   +1 more source

Exploring Quantity and Diversity of Informal Digital Learning of English (IDLE): A Review of Selected Paper

open access: yesUtamax, 2019
This article reviews research on informal digital English (IDLE) learning that has increased in the field of English language teaching to other language speakers and computer-assisted language learning written by Ju Seong Lee (2019), entitled Quantity ...
Nofita Sari Gowasa   +2 more
doaj   +1 more source

Nothing Great Is Easy [PDF]

open access: yes, 2014
A solo exhibition of 13 pieces of art work. Nothing Great is Easy is an exhibition of sculpture, film, drawing and photography that proposes reconstructed narratives using the sport of swimming and in particular the collective interaction and identity
Stansbie, Lisa
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Concurrent extensions to the FORTRAN language for parallel programming of computational fluid dynamics algorithms [PDF]

open access: yes
Experiments were conducted at NASA Ames Research Center to define multi-tasking software requirements for multiple-instruction, multiple-data stream (MIMD) computer architectures.
Weeks, Cindy Lou
core   +1 more source

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