Results 101 to 110 of about 764,282 (354)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Distorsi citra tubuh, perilaku makan, dan fad diets pada remaja putri di Yogyakarta
Background: Vast changing environment and culture including mass media which commonly shows models with a very slim body may cause teenage girls feel fatty and not confident despite their normal body weight.
Atika Sulistyan +2 more
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Positive Feedback on Appearance, Value Placed on Appearance, and Need for Disordered Eating Behavior among Undergraduate Females [PDF]
Negative feedback about appearance is often cited as a major contributor to unhealthy eating behavior among women. The present study examined whether positive feedback about appearance may also be associated with disordered eating behavior, particularly ...
Conley \u2704, Amanda R.
core +1 more source
Hoarding Symptoms Are Not Exclusive to Hoarders [PDF]
Hoarding Disorder (HD) was originally conceptualized as a subcategory of Obsessive Compulsive Disorder (OCD), and numerous studies have in fact focused exclusively on investigating the comorbidity between OCD and HD.
Bottesi, Gioia +3 more
core +2 more sources
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Transtheoretical model approach in eating behavior [PDF]
O estudo do comportamento alimentar tem despertado grande interesse por se tratar de um elemento importante para o sucesso de intervenções nutricionais. Considerando-se a complexidade do tema e as inúmeras influências a que está submetido, sugere-se que ...
Bertolin, Maria Natacha Toral +1 more
core +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Background: the violations of eating behavior began to be actively studied since the mid-20th century. In recent years, researchers from different countries have found new evidence of the role of eating behavior, the patient's eating habits in the ...
Olga V. Filatova +4 more
doaj +1 more source
Background Binge eating behavior is highly likely to progress to an eating disorder, with female students particularly at risk. Objective This study aimed to verify the effect of a binge eating behavior management program, based on rational emotive ...
Jiwon Yang, Kuem Sun Han
doaj +1 more source

