Results 41 to 50 of about 423,188 (304)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Cluster analysis in gambling disorder based on sociodemographic, neuropsychological, and neuroendocrine features regulating energy homeostasis

Comprehensive Psychiatry
Background: The heterogeneity of gambling disorder (GD) has led to the identification of different subtypes, mostly including phenotypic features, with distinctive implications on the GD severity and treatment outcome.
Isabel Baenas, Bernat Mora-Maltas, Mikel Etxandi, Ignacio Lucas, Roser Granero, Fernando Fernández-Aranda, Sulay Tovar, Neus Solé-Morata, Mónica Gómez-Peña, Laura Moragas, Amparo del Pino-Gutiérrez, Javier Tapia, Carlos Diéguez, Anna E. Goudriaan, Susana Jiménez-Murcia   +14 more
doaj   +1 more source

Cognitive behavior therapy for eating disorders versus normalization of eating behavior

Physiology & Behavior, 2017
We examine the science and evidence supporting cognitive behavior therapy (CBT) for the treatment of bulimia nervosa and other eating disorders. Recent trials focusing on the abnormal cognitive and emotional aspects of bulimia have reported a remission rate of about 45%, and a relapse rate of about 30% within one year.
Södersten, P., Bergh, C., Leon, M., Brodin, U., Zandian, M.   +4 more
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

An evidence review of the association of immune and inflammatory markers with obesity-related eating behaviors

Frontiers in Immunology, 2022
BackgroundEating behaviors contribute to disproportionate energy intake and are linked to the development of obesity. Animal studies support the role of inflammatory cytokines and chemokines in the regulation of obesity-related eating behaviors and offer
Ying Meng, Amber Kautz
doaj   +1 more source

Binge Eating Disorder Mediates Links between Symptoms of Depression and Anxiety and Caloric Intake in Obese Women [PDF]

, 2012
Despite considerable comorbidity between mood disorders, binge eating disorder (BED), and obesity, the underlying mechanisms remain unresolved. Therefore, the purpose of this study was to examine models by which internalizing behaviors of depression and ...
Bartholome, Lindsay T., Latendresse, Shawn J., Peterson, Roseann E., Raymond, Nancy C., Warren, Cortney S.   +4 more
core   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Eating behaviors, dietary patterns and weight status in emerging adulthood and longitudinal associations with eating behaviors in early childhood

International Journal of Behavioral Nutrition and Physical Activity, 2022
Background Eating behaviors may contribute to differences in body weight and diet over time. Our study aims to examine how eating behaviors of young adults relate to their current weight status and dietary patterns and to explore longitudinal ...
Lise Dubois, Brigitte Bédard, Danick Goulet, Denis Prud’homme, Richard E. Tremblay, Michel Boivin   +5 more
doaj   +1 more source

Relationship between eating behaviors and physical activity of preschoolers and their peers: a systematic review [PDF]

, 2016
: Objectives: Children learn by observing and imitating others, meaning that their eating behaviors and physical activity may be influenced by their peers.
A Bandura, C Barbour, CC Voorhees, D Schunk, Denise Donovan, G Ladd, J Castro de, JC Conger, JC Lumeng, JC Schwarz, JM Castro de, K Duncker, LL Moore, M Okun, M Shields, Mathieu F. Bélanger, Natalie Carrier, P Anderson, R Harbour, RC Klesges, RE Andersen, RE LaPorte, S Bannoff, Stéphanie A. Ward, TG Plante, V Mikkilä, WO Eaton   +26 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source