Results 61 to 70 of about 1,470,901 (299)

Psychiatric comorbidity and maternal distress among adolescent eating disorder patients: a comparison with substance use disorder patients

, 2017
High rates of comorbidity are found among eating disorder (ED) patients, which may negatively affect treatment outcome and prognosis. However, there is a shortage of studies in Spain using clinician administered interviews to assess rates of comorbidity ...
Graell, Montserrat, Parks, Melissa, Brugnera, Agostino, Anastasiadou, Dimitra Tatiana, Sepúlveda, Ana R.   +4 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Reimagining care: effectiveness of modifying an adolescent eating disorder intensive service

BJPsych Bulletin
Aims and method The COVID-19 pandemic prompted a surge in adolescent eating disorders and rapid changes in the delivery of intensive community treatments.
Ellen Hayes, Nicola Tweedy, Victoria Chapman   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The economic impact of eating disorders in children and youth in Canada: a call to action to improve youth eating disorder research and care

Journal of Eating Disorders, 2023
The COVID-19 pandemic has led to an unprecedented rise in rates and symptoms of eating disorders among Canadian youth. To date, there is a lack of national surveillance and costing data in Canada to inform policymakers and healthcare leaders on how to ...
Jennifer S. Coelho, Linda Booij, Debra K. Katzman, Gina Dimitropoulos, Nicole Obeid   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

SipNose-topiramate: a potential novel approach to binge eating management

Journal of Eating Disorders, 2023
Background Binge-eating disorder) BED) is the most common eating disorder in the United-States. Daily, orally administered topiramate has shown BED treatment efficacy, with two major limitations: frequent and severe side effects and slow time-to-effect ...
Ayala Kobo-Greenhut, Adit Zohar-Beja, Liron Hadar, Lior Itzhaki, Avraham Karasik, Yoseph Caraco, Hilel Frankenthal, Daniel Shahaf, Dana Ekstein, Iris Shichor, Eitan Gur   +10 more
doaj   +1 more source

Negative mood induction effects on problem-solving task in women with eating disorders: a multi-method examination [PDF]

, 2022
BACKGROUND: The effects of negative affect on problem-solving and its psychophysiological correlates are poorly understood in eating disorder populations.
French, Elan N., Arlt, Jean M., Chen, Eunice Y., Yiu, Angelina, Eneva, Kalina, Chen, Eunice, Chen|   +6 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

An investigation of the role of thought-shape fusion in disordered eating

, 2013
A literature review presents research investigating the role of thought-shape fusion (TSF) in eating disorder psychopathology. As TSF is a relatively new area of research, reviewing literature at this stage aimed to identify methodological issues ...
Pisarski, Stephanie
core   +1 more source