Results 31 to 40 of about 10,694 (250)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Delayed Diagnoses: Nonspecific Findings and Diagnostic Challenges in Eating Disorders

Case Reports in Medicine, 2009
Objective. Eating disorders commonly present with nonspecific findings, masquerading as other, more common etiologies of malnutrition and wasting. In low-prevalence populations, these ambiguities can complicate clinicians’ diagnostic reasoning, resulting
Dan Schwarz, Kathryn L. Ponder, Edward R. Feller   +2 more
doaj   +1 more source

Effect of yoga in the treatment of eating disorders: A single-blinded randomized controlled trial with 6-months follow-up

International Journal of Yoga, 2018
Aim of the Study: The aim of this study is to examine the effect of yoga treatment of eating disorders (EDs). Methods: Adult females meeting the Diagnostic and Statistical Manual-IV criteria for bulimia nervosa or ED not otherwise specified (n = 30) were
Kari Ebbesen Karlsen, Karianne Vrabel, Solfrid Bratland-Sanda, Pål Ulleberg, Kirsten Benum   +4 more
doaj   +1 more source

Don't forget EDNOS (eating disorder not otherwise specified): patterns of service use in an eating disorders service [PDF]

Psychiatric Bulletin, 2005
Aims and MethodThe aim of the study was to track service consumption in adult referrals to a specialised NHS eating disorders service over a 3-year period. We examined clinical records of a year's cohort (1999) of 147 referrals (96% female) assessed from the local catchment area.ResultsThe most common diagnostic group (42.8%) presented with some form ...
Eric J. Button, Elizabeth Benson, Claire Nollett, Robert L. Palmer   +3 more
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Self-injurious behaviour in patients with anorexia nervosa: a quantitative study

Journal of Eating Disorders, 2018
Background Many patients with an eating disorder report difficulties in regulating their emotions and show a high prevalence of self-injurious behaviour.
Linda Smithuis, Nienke Kool-Goudzwaard, Janneke M. de Man-van Ginkel, Harmieke van Os-Medendorp, Tamara Berends, Alexandra Dingemans, Laurence Claes, Annemarie A. van Elburg, Berno van Meijel   +8 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

DIMENSIONS OF COMPULSIVE EXERCISE ACROSS EATING DISORDER DIAGNOSTIC SUBTYPES AND THE VALIDATION OF THE SPANISH VERSION OF THE COMPULSIVE EXERCISE TEST.

Frontiers in Psychology, 2016
Objectives: Compulsive exercise in eating disorders has been traditionally considered as a behavior that serves the purpose of weight/shape control. More recently, it has been postulated that there may be other factors that drive the compulsive need to ...
Sarah Sauchelli, Sarah Sauchelli, Jon Arcelus, Jon Arcelus, Roser Granero, Roser Granero, Susana Jiménez-Murcia, Susana Jiménez-Murcia, Susana Jiménez-Murcia, Zaida Aguera, Zaida Aguera, Amparo Del Pino-Gutiérrez, Amparo Del Pino-Gutiérrez, Fernando Fernandez-Aranda, Fernando Fernandez-Aranda, Fernando Fernandez-Aranda   +15 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source