Results 241 to 250 of about 243,728 (328)

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue

open access: yesAdvanced Science, EarlyView.
This study demonstrates that MTCH2 acts as an evolutionarily conserved regulator of energy homeostasis across Drosophila, rodents, and humans. Adipose‐specific MTCH2 ablation enhances brown/beige adipose thermogenesis through Bcl‐2‐dependent autophagy, promoting energy expenditure and counteracting obesity‐associated metabolic disorders. These findings
Xin‐Yuan Zhao   +17 more
wiley   +1 more source

Early intervention for eating disorders. [PDF]

open access: yesCurr Opin Psychiatry
Mills R, Hyam L, Schmidt U.
europepmc   +1 more source

Highly Oriented SiC@SiO2 Ceramic Fiber Aerogels with Good Anisotropy of the Thermal Conductivity and High‐Temperature Resistance

open access: yesAdvanced Science, EarlyView.
The anisotropic‐structure SiC@SiO2 ceramic fiber aerogels feature aligned layers stacking layer‐by‐layer with the same direction and highly oriented 1D fibers inside each layer, resulting in an anisotropy factor as high as 5.08. Not only does it have 60% high recoverable deformation, but it also shows great promise for thermal protection in extreme ...
Zheng Zhang   +7 more
wiley   +1 more source

Updated Insights Into the Mechanism of Salt‐Induced Aggregation‐Based Single‐Molecule Surface‐Enhanced Raman Spectroscopy

open access: yesAdvanced Science, EarlyView.
A salt‐gradient model is proposed to investigate the physical nature and update insights into the single molecule surface‐enhanced Raman spectroscopy (SM‐SERS). The release of Ag+ ions from the Ag NPs and the final formation of precipitate of AgCl with Cl‐ on the surface of the aggregated Ag NPs plays as the active and packaging shell to improve the SM‐
Lingwei Li   +8 more
wiley   +1 more source

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

open access: yesAdvanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen   +9 more
wiley   +1 more source

Exploring the COVID-19 pandemic's influence on eating disorders: insights from an Italian residential center. [PDF]

open access: yesFront Psychol
Monaco F   +19 more
europepmc   +1 more source

METTL14‐Induced M6A Methylation Increases G6pc Biosynthesis, Hepatic Glucose Production and Metabolic Disorders in Obesity

open access: yesAdvanced Science, EarlyView.
It is shown that obesity is associated with increases in hepatic METTL14 and m6A methylation of G6pc transcript. YTHDF1 and YTHDF3 bind to m6A‐marked G6pc mRNA to increase its synthesis. Hepatocyte‐specific deletion of Mettl14 decreases G6pc m6A methylation, G6pc biosynthesis, and G6pc‐mediated gluconeogenesis, alleviating glucose metabolic defects in ...
Qiantao Zheng   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy