Results 191 to 200 of about 13,237 (253)

Self-harm in individuals who experience binge eating disorder: A systematic review and meta-analysis. [PDF]

J Eat Disord
Moore E, Clements C, Flattery E, Bhutta A, Taylor P.   +4 more
europepmc   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Model‐Enabled Knowledge Transfer Across Cell Lines, Culture Scales and Conditions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Mechanistic models are central to quantitative understanding and optimization of Chinese hamster ovary (CHO) cell culture processes, but their utility is often restricted by parameter sets calibrated for specific cell lines, scales, or operating conditions.
Luxi Yu, Antonio del Rio Chanona, Cleo Kontoravdi   +2 more
wiley   +1 more source

Time to notice neurodiversity in eating disorder services: a three-year real-world analysis of autism, ADHD, and AuDHD. [PDF]

Front Psychiatry
Makin L, Allen K, Tchanturia K.
europepmc   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Metabolomic ageing across mental and behavioural disorders. [PDF]

BMJ Ment Health
Mutz J, Gilchrist L, Allegrini AG, Sanchez Roige S, Lewis CM.   +4 more
europepmc   +1 more source

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

Biological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief, Sandra Bouwhuis, Anja Globig, Anne Günther, Wouter Courtens   +4 more
wiley   +1 more source

Efficacy of a low-FODMAP diet in children with irritable bowel syndrome and functional abdominal pain-not otherwise specified: a randomized controlled trial with early termination. [PDF]

Front Pediatr
Stróżyk A, Horvath A, Kozłowska-Jalowska A, Muir J, Szajewska H.   +4 more
europepmc   +1 more source

Orchard netting impacts on biodiversity leading to cascading effects at the ecosystem level

Biological Reviews, EarlyView.
ABSTRACT Agriculture must ensure food production without further compromising the ecosystem functions upon which it depends. Agricultural practices should therefore avoid harming farmland biodiversity, especially of taxa that supply the key ecosystem services (e.g.
Corrado Alessandrini, Karan Sethi, Emanuela Granata, Ekaterina Mogilnaia, Valeria Vitangeli, Giovanni Zanfei, Chiara Fedrigotti, Paolo Biella, Dino Scaravelli, Luigi Marchesi, Péter Batáry, Diego Rubolini, Paolo Pedrini, Mattia Brambilla   +13 more
wiley   +1 more source

Prevalence of Eating Disorders in People With Borderline Personality Disorder: A Systematic Review and Meta-Analysis. [PDF]

Clin Psychol Psychother
Paudex T, Endomba FT, Forestier N, Pierandrei A, Chauvet-Gélinier JC, Pinoit JM.   +5 more
europepmc   +1 more source