An EAV-HP Insertion in 5′ Flanking Region of SLCO1B3 Causes Blue Eggshell in the Chicken
PLoS Genetics, 2013 The genetic determination of eggshell coloration has not been determined in birds. Here we report that the blue eggshell is caused by an EAV-HP insertion that promotes the expression of SLCO1B3 gene in the uterus (shell gland) of the oviduct in chicken ...
Lujiang Qu +2 more
exaly +2 more sources
Role of Unfolded Protein Response in the Apoptosis Induced by Alphaarterivirus: IRE1α as an Essential Pathway for In Vitro Replication [PDF]
VirusesThe perturbation of ER homeostasis by viral infection gives rise to the unfolded protein response (UPR), characterized by the activation of three signaling pathways.
Santiago Emanuel Colina +4 more
doaj +2 more sources
Adverse childhood experiences and elder abuse victimization nexus: A systematic review and meta-analysis. [PDF]
PLoS ONEAdverse childhood experiences (ACEs) are important life course events that can influence elder abuse victimisation (EAV) among older adults. This systematic review and meta-analysis aimed to provide synthesised and consolidated evidence on the existing ...
Kofi Awuviry-Newton +4 more
doaj +2 more sources
Whole-body vibration exposure and its predictors among food delivery riders in eastern Peninsular Malaysia [PDF]
Journal of Public Health ResearchBackground: Chronic exposure to whole-body vibration (WBV) is a significant contributor to work-related musculoskeletal disorders (WMSDs) among motorcyclists.
Aziah Daud +6 more
doaj +2 more sources
The Electroanatomic Volume of the Left Atrium as a Determinant of Recurrences in Patients with Atrial Fibrillation After Pulmonary Vein Isolation: A Prospective Study [PDF]
BiomedicinesBackground/Objectives: Catheter ablation for atrial fibrillation (AF) is a well-established therapeutic approach for maintaining sinus rhythm, though its efficacy remains suboptimal in certain patients.
Amaia Martínez León +6 more
doaj +2 more sources
Endoscopy-assisted vitrectomy for severe ocular penetrating trauma with corneal opacity [PDF]
International Journal of OphthalmologyAIM: To assess the utility and efficiency of endoscopy-assisted vitrectomy (EAV) for the treatment of corneal opacity in severe ocular trauma. METHODS: Patients who underwent fundus examination using a preoperative slit lamp and intraoperative endoscopy,
Yong-Zhen Yu +6 more
doaj +2 more sources
Generation of functional noncanonical donor splice sites by +2T variants in breast cancer susceptibility genes: impact on clinical interpretation. [PDF]
J PatholAbstract Splicing dysregulation is a relevant mechanism of pathogenicity for variants in disease susceptibility genes. Variants affecting the critical intronic +1 and +2 GT nucleotides of the 5’ splice sites (5'ss) are generally strong indicators of pathogenicity.
Llinares-Burguet I +7 more
europepmc +2 more sources