Results 21 to 30 of about 2,782 (162)

A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya, Venkata Yellepeddi, Ann Marie B. Prazak, Mathangi Gopalakrishnan   +3 more
wiley   +1 more source

Frizyalı Ebe Catharina Schrader’in “Mother and Child Were Saved”Adlı Kitabında Yer Alan Doğum Anılarının İncelenmesi (1693-1740)

Lokman Hekim Dergisi
Amaç: Frizyalı Ebe Catharina Schrader’in “Mother and Child Were Saved”adlı kitabında yer alan doğum deneyimlerine ilişkin anıları ebeliğin tarihsel gelişimi açısından önemli bir kaynaktır.
Ebru Gözüyeşil, Rukiye Sülü Dursun
doaj   +1 more source

Bloodstream-To-Eye Infections Are Facilitated by Outer Blood-Retinal Barrier Dysfunction.

PLoS ONE, 2016
The blood-retinal barrier (BRB) functions to maintain the immune privilege of the eye, which is necessary for normal vision. The outer BRB is formed by tightly-associated retinal pigment epithelial (RPE) cells which limit transport within the retinal ...
Phillip S Coburn, Brandt J Wiskur, Frederick C Miller, Austin L LaGrow, Roger A Astley, Michael H Elliott, Michelle C Callegan   +6 more
doaj   +1 more source

Endogenous endophthalmitis caused by group B streptococcus; case reports and review of 35 reported cases

BMC Ophthalmology, 2020
Background Group B streptococcus (GBS), a gram-positive coccus that occasionally causes neonatal sepsis or invasive infection in the elderly, has been considered a rare cause of endogenous bacterial endophthalmitis (EBE).
Masaaki Yoshida, Shunji Yokokura, Takashi Nishida, Kiyofumi Mochizuki, Takashi Suzuki, Kazuichi Maruyama, Takaaki Otomo, Koji M. Nishiguchi, Hiroshi Kunikata, Toru Nakazawa   +9 more
doaj   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu, Zihan Qin, Logan S. Smith, Jeong M. Park, Hao‐Jie Zhu   +4 more
wiley   +1 more source

Pharmacokinetics and pharmacodynamics of intravenous and oral (S)‐ketamine: Investigating metabolite contribution to subjective effects

British Journal of Clinical Pharmacology, EarlyView.
Aims Oral administration of (S)‐ketamine for treatment‐resistant depression (TRD), as alternative to the registered intranasal or off‐label intravenous administrations, has high potential. However, it is characterized by an extensive first‐pass metabolism, resulting in low (S)‐ketamine exposure and high levels of active metabolites, including (S ...
Marije E. Otto, Gabriël E. Jacobs, Joost C. van Mechelen, Laura G. J. M. Borghans, Johan G. C. van Hasselt, Linda B. S. Aulin   +5 more
wiley   +1 more source

Antiosteoarthritis activities of 70% ethanol extract of Eleutherine bulbosa (mill.) urb. bulb on rats monosodium iodoacetate-induced osteoarthritis

Journal of Public Health in Africa, 2023
Background: Osteoarthritis (OA) is a common degenerative joint situation that induces pain and disability in the elderly. Traditionally, Eleutherine bulbosa bulb from Pasuruan, East Java, is used to treat many diseases, also as an anti-inflammatory ...
Riza A. Sari, Fina Luthfiana, Irawati Sholihah, Katsuyoshi Matsunami, Sukardiman Sukardiman, Retno Widyowati   +5 more
doaj   +1 more source

Fabrication of amorphous lamellar freestanding poly(N‐dodecyl acrylamide) films and their mechanical properties

Polymer International, EarlyView.
A freestanding film of completely uniaxially oriented amorphous lamellae was produced. The film exhibited enhanced tensile strength with increasing orientation of the lamella. Abstract An amorphous lamellar freestanding film composed of poly(N‐dodecyl acrylamide) (pDDA) was prepared by annealing a micrometer‐thick film under humid conditions (humid ...
Yuki Koizumi, Yoshimasa Matsuo, Akito Masuhara, Hinako Ebe, Yuya Ishizaki‐Betchaku, Shusaku Nagano, Jun Matsui   +6 more
wiley   +1 more source

Midwives’ Knowledge Level About Newborn Individualized Development Care and Assessments Program

Ebelik ve Sağlık Bilimleri Dergisi
Objective: The Newborn Individualized Developmental Care and Assessment Program (NIDCAP) has been developed to create a common point to enhance the parameters of neonatal health by Als et al.
Handan Özcan, Nükhet Kaçar
doaj   +1 more source

Developing relevant community mental health programmes in North India: five questions we ask when co-producing knowledge with experts by experience

BMJ Global Health, 2023
Knowledge co-production can improve the quality and accessibility of health, and also benefit service users, allowing them to be recognised as skilled and capable.
Kaaren Mathias, Sumeet Jain, Pooja Pillai, Meenal Rawat, Rachelle Anne Martin, Kakul Shelly   +5 more
doaj   +1 more source