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Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
The Epstein-Barr virus (EBV) is an oncogenic Herpes virus involved in the induction of a variety of human tumours. It was the first virus found to encode microRNAs (miRNAs). MiRNAs are short, non-coding RNAs that in most cases negatively regulate gene expression at the post-transcriptional level.
Stephanie, Barth +2 more
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The Epstein-Barr virus (EBV) is an oncogenic Herpes virus involved in the induction of a variety of human tumours. It was the first virus found to encode microRNAs (miRNAs). MiRNAs are short, non-coding RNAs that in most cases negatively regulate gene expression at the post-transcriptional level.
Stephanie, Barth +2 more
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Immune defence against EBV and EBV-associated disease
Current Opinion in Immunology, 2011Epstein-Barr virus (EBV), a B-lymphotropic herpesvirus widespread in the human population and normally contained as an asymptomatic infection by T cell surveillance, nevertheless causes infectious mononucleosis and is strongly linked to several types of human cancer. Here we describe new findings on the range of cellular immune responses induced by EBV
Heather M, Long +2 more
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EBV-positive mucocutaneous ulceration
The Annals of The Royal College of Surgeons of England, 2021Ulceration of the oral cavity is common and a frequent reason for referral to secondary and tertiary centres. Epstein–Barr virus (EBV)-related mucocutaneous ulceration, however, is a rare cause of oral ulceration that has been described only recently.
A, Jivraj +4 more
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2015
Although a role of EBV in autoimmunity is biologically plausible and evidence of altered immune responses to EBV is abundant in several autoimmune diseases, inference on causality requires the determination that disease risk is higher in individuals infected with EBV than in those uninfected and that in the latter it increases following EBV infection ...
Alberto, Ascherio, Kassandra L, Munger
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Although a role of EBV in autoimmunity is biologically plausible and evidence of altered immune responses to EBV is abundant in several autoimmune diseases, inference on causality requires the determination that disease risk is higher in individuals infected with EBV than in those uninfected and that in the latter it increases following EBV infection ...
Alberto, Ascherio, Kassandra L, Munger
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EBV-Directed T Cell Therapeutics for EBV-Associated Lymphomas
2016Epstein Barr virus (EBV) is a human gamma herpes virus that establishes latency in B cells after primary infection. EBV generally only causes a mild, self-limiting viral illness but is also associated with several malignancies including posttransplantation lymphoproliferative disorder in the immunosuppressed host as well as Hodgkin and non-Hodgkin ...
Lauren P, McLaughlin +3 more
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2001
The Epstein-Barr virus (EBV) can choose between two alternative life styles. It infects B lymphocytes, transforming them into lymphoblastoid lines and, in contrast to neurotropic herpesviruses such as herpes simplex virus type I that establish latency in nondividing neurons, must maintain its latent genomes in cells that have the potential to divide ...
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The Epstein-Barr virus (EBV) can choose between two alternative life styles. It infects B lymphocytes, transforming them into lymphoblastoid lines and, in contrast to neurotropic herpesviruses such as herpes simplex virus type I that establish latency in nondividing neurons, must maintain its latent genomes in cells that have the potential to divide ...
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Mutation Research/Reviews in Genetic Toxicology, 1989
Shuttle vectors based on Epstein-Barr virus (EBV) replicate autonomously in the nuclei of human cells. These vectors represent reasonable models for chromosomes, have low background mutation frequencies, and have been useful for studying induced mutation in human cells. Two improvements in the EBV vector system are discussed.
S B, Haase +3 more
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Shuttle vectors based on Epstein-Barr virus (EBV) replicate autonomously in the nuclei of human cells. These vectors represent reasonable models for chromosomes, have low background mutation frequencies, and have been useful for studying induced mutation in human cells. Two improvements in the EBV vector system are discussed.
S B, Haase +3 more
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Identification of EBV transforming genes by recombinant EBV technology
Seminars in Cancer Biology, 2001Epstein-Barr virus (EBV) is able to infect primary B-lymphocytes but usually does not proceed to replicate more virions. Instead, EBV persists as an incomplete virus and expresses 12 gene products that transform the growth of these cells into continuously proliferating lymphoblastoid cell lines. Because EBV is associated with several human malignancies,
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EuropaBON/EBV-Descriptions: EuropaBON EBVs List Descriptions
The essential biodiversity variables (EBVs) are the minimum set of variables needed to quantitatively measure changes in biodiversity and ecosystem service delivery systematically over time and space, with an overarching role of standardising and coordinating biodiversity monitoring.Quoss, Luise +2 more
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