Results 101 to 110 of about 1,206,353 (285)

Structure of EC and EC-like compounds.

open access: yes, 2020
Structure of EC and EC-like compounds.
Doron Steinberg (559690)   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Increased Serum Calcium Level Promotes the Risk of Lymph Node Metastasis in Endometrial Cancer

open access: yesCancer Management and Research, 2020
Xing-Chen Li,1,* Yang-Yang Dong,1,* Yuan Cheng,1 Jing-Yi Zhou,1,2 Xiao Yang,1 Bo-Qiang Shen,1 Xiao-Tong Wu,1,2 Xiao-Ping Li,1 Jian-Liu Wang1,2 1Department of Obstetrics and Gynecology, Peking University People’s Hospital, Beijing 100044, People ...
Li XC   +8 more
doaj  

The Association Between Nicotine Dependence and Mental Health in the General Population of Saudi Arabia: A Cross-Sectional Analytical Study

open access: yesInternational Journal of General Medicine, 2023
Danah Abdullah Albarrak,1 Abdulrahman Bandar Alotaibi,2 Roaa Faisal Alotaibi,3 Sara Hussain Alramadhan,3 Alhanouf Ibrahim Bin Muhanna,1 Abdulrahman Mohammed Aldehan,2 Khalid A Bin Abdulrahman4 1College of Medicine, King Saud bin Abdulaziz University for ...
Albarrak DA   +6 more
doaj  

EC-081118S

open access: yes
EC explica por que tiene que componer su ...
Swintha, EC
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Effects of Biochar Application on the Dynamic of Soil Moisture-Temperature-Salt in Degraded Mollisols During Freezing Period

open access: yesShuitu Baochi Xuebao
[Objective] Biochar application can change soil physicochemical properties. The study of the effects of different biochar application methods on soil moisture, temperature and electrical conductivity (EC) distribution, which can provide basis for the ...
WEI Zhimiao   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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