Results 151 to 160 of about 1,206,353 (285)

DHX9 Inhibition Enhances Paclitaxel Sensitivity by Inducing Mitotic Failure in Ovarian and Endometrial Cancers. [PDF]

Mol Cancer Ther
Huang TT, Nair JR, Bowen C, Castro J, Nousome D, Nayak S, Silver SJ, Lee JM.   +7 more
europepmc   +1 more source

Por un gobierno de la economía en la Unión Europea

, 2017
Para el estado moderno, la economía siempre ha sido un fenómeno complejo de gobernar. Prueba de ello son las Constituciones del ‘900 (como aquella italiana) que por primera vez propusieron una más o menos articulada estructura jurídica de la economi ...
EC Raffiotta
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Endothelial progenitor cell susceptibility to DNA damaging and DDR-modulating compounds determines endothelial differentiation accuracy. [PDF]

Stem Cell Res Ther
Federmann S, Westerhoff M, Reichert AS, Fritz G.   +3 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Ethics review of multi-centre trials in India: a survey of researchers and ethics committee members on perspectives, challenges, and opportunities. [PDF]

BMC Med Ethics
Noronha NB, Cherian JJ, Kumar G, Anand T, Roy S, Turuk A, Gangwar M, Chalisserry EP, Sinha S, Poomali A, Mathur R, Gupta TM, Mukherjee A.   +12 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Endothelial KLF4 depletion drives age-related neurovascular dysfunction and neuropsychiatric impairment. [PDF]

Proc Natl Acad Sci U S A
Dhar M, Vázquez-Rosa E, Chaubey K, Miller E, Corella SG, Chakraborty S, Tripathi SJ, Das T, Liao X, Alosman MA, Fang H, Koh Y, Sridharan PS, Franke K, Cintrón-Pérez CJ, Cintrón-Pérez AA, Tomco T, Indrakumar V, Rubin PJ, Pieper JG, Ashiku LA, Shin MK, Tang X, Padmanabhan R, Haragopal H, Flanagan ME, Jain R, Winters BD, Wilson BM, Paul BD, Jain MK, Pieper AA.   +31 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Diagnosis and management of immune effector cell-associated enterocolitis after ciltacabtagene autoleucel. [PDF]

Blood Adv
Lim KJC, Lee HE, Chen ZE, Bledsoe A, Parrondo R, Chhabra S, Dooley K, De Menezes Silva Corraes A, Gertz M, Hwa L, Stephens H, Kapoor P, Tan M, Kourelis T, Warsame R, Cook J, Binder M, Bergsagel PL, Yadav U, Wiedmeier-Nutor E, Geyer S, Ailawadhi S, Fonseca R, Kumar S, Chowla N, Lin Y.   +25 more
europepmc   +1 more source