Results 181 to 190 of about 389,890 (305)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Dysfunctional connectivity within hippocampal and entorhinal networks underlies early-life iron deficiency induced social recognition deficits, a preliminary study. [PDF]

Sci Rep
Ding A, Tan T, Liu P, Li X, Zhu M, Liu H, Wang Y, Chen Y, Tang YP.   +8 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Changes in postural control in older adults: a five-year longitudinal study. [PDF]

Sci Rep
Nohelova D, Vuillerme N, Bizovska L, Janura M, Svoboda Z.   +4 more
europepmc   +1 more source

PWM Rotation of Brushless DC Motor EC-32 by PIC16F88 and Rotation in terms of Combinational Logic Circuit

PWM Rotation of Brushless DC Motor EC-32 by PIC16F88 and Rotation in terms of Combinational Logic Circuit
The brushed direct current (DC) motor rotates by applying DC voltage. The brushless DC (BLDG) motor also known as electronically commutated motors (ECMs, EC motors) is categorized into synchronous motors. The method of pulse width modulation (PWM) rotation of the brushless DC motor seems to be not straightforward.
openaire  

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Hyperammonemia reduces the populations of beneficial lactobacilli and bifidobacteria, disrupting the metabolic balance of the gut microbiome in rats. [PDF]

Front Microbiol
Giner-Pérez L, Felipo V, Izquierdo-Altarejos P, Llansola M, Pérez Martínez G.   +4 more
europepmc   +1 more source

Implementing the Community Lisbon programme: A strategy for the simplification of the regulatory environment. Communication from the Commission. COM (2005) 535 final, 25 October 2005 [PDF]

, 2005

core  

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Development of a training-oriented wearable knee joint exoskeleton for forming a scientific force application pattern in squat tasks. [PDF]

Front Bioeng Biotechnol
Chang S, Feng F, Li Z, Yu Y.
europepmc   +1 more source